Paper Title
Synthesis and evaluation of naphthyl-xanthine derivatives as anti-obesity agents
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Registration ID: IJNRD_300951
Published ID: IJNRD2410024
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Keywords
Xanthine, 5-hydroxytryptamine, anti-obesity, naphthyl, hypophagic
Abstract
The objective of this work was to synthesize naphthyl-xanthine derivatives and evaluate the anti-obesity action of the synthesized compounds. The synthesized compounds A1-5 were cream to light brown in color and obtained in 69-715 % yields and were soluble in chloroform. The confirmation of the structures of the compounds was done by 1H-NMR, mass and IR spectral study. A1-5 were found to be hypophagic and restrict the intake of food by the mice and the hyperphagic effect of (±) - 8- OH-DPAT was antagonized by both the synthesized compound.
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How To Cite (APA)
Md Abid Sheikh, Ankit Diwan, Mahima Patawardhan, & Kuldeep Ganju (October-2024). Synthesis and evaluation of naphthyl-xanthine derivatives as anti-obesity agents. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(10), a197-a206. https://ijnrd.org/papers/IJNRD2410024.pdf
Issue
Volume 9 Issue 10, October-2024
Pages : a197-a206
Other Publication Details
Paper Reg. ID: IJNRD_300951
Published Paper Id: IJNRD2410024
Research Area: Pharmacy All
Author Type: Indian Author
Country: Bhopal, Madhya Pradesh, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2410024.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2410024
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