Paper Title
MICROBEADS - A PROMISING TECHNOLOGY FOR CONTROLLED DRUG DELIVERY: A REVIEW
Article Identifiers
Authors
Dr.Christopher Vimalson.D , Mrs.Mumtaj.J , T.Gowrishankar , Jannathul Firthosh.S , Bavadharani.R, Karthikeyan.R, Nigil.M, Dr.Alagarraja.M
Keywords
microbeads, controlled release, drug delivery, polymer-based carriers.
Abstract
Microbeads have emerged as a versatile and effective platform for controlled drug delivery, offering advantages such as improved bioavailability, reduced dosing frequency, and enhanced therapeutic efficacy. This review provides a comprehensive overview of recent advancements in the formulation and evaluation of microbeads for pharmaceutical applications. We discuss various polymers utilized in microbeads preparation, including natural (e.g., alginate, chitosan) and synthetic (e.g., poly (lactic-co-glycolic acid), Eudragit) materials, and their impact on drug release kinetics. The article examines different techniques for microbeads fabrication, such as Ionotropic gelation, emulsification, and spray drying, highlighting their principles, advantages, and limitations. Additionally, we explore strategies for optimizing drug loading, encapsulation efficiency, and release profiles. The review also covers state-of-the-art characterization methods for evaluating microbeads properties, including size distribution, surface morphology, zeta potential, and in vitro drug release studies. Furthermore, we address the challenges in microbeads formulation and potential solutions, as well as regulatory considerations for their development. Finally, we provide insights into emerging trends and future directions in microbeads technology for drug delivery. This comprehensive review aims to serve as a valuable resource for researchers and formulators working on microbeads-based drug delivery systems.
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How To Cite (APA)
Dr.Christopher Vimalson.D, Mrs.Mumtaj.J, T.Gowrishankar, Jannathul Firthosh.S, & Bavadharani.R, Karthikeyan.R, Nigil.M, Dr.Alagarraja.M (September-2024). MICROBEADS - A PROMISING TECHNOLOGY FOR CONTROLLED DRUG DELIVERY: A REVIEW. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(9), b391-b400. https://ijnrd.org/papers/IJNRD2409147.pdf
Issue
Volume 9 Issue 9, September-2024
Pages : b391-b400
Other Publication Details
Paper Reg. ID: IJNRD_300117
Published Paper Id: IJNRD2409147
Downloads: 000121983
Research Area: Pharmacy All
Country: Coimbatore, Tamil Nadu, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2409147.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2409147
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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