Paper Title
Toxicokinetic evaluation in preclinical studies and applications of toxicokinetic
Article Identifiers
Authors
Ms. Jadhav Supriya Kailas , Mr. Kale Atulkumar Bajirao , Miss. Pooja Sudam Waje , Ms.Deore Sonika Balchand , Mr. Aniket Dhulap
Keywords
Toxicokinetic, Area Under the Curve, Bioavailability, Metabolic Rate Constant
Abstract
Toxicokinetic assessment is both a monitoring tool and a scientific necessity in the drug development process. Toxicokinetic involves the generation of dynamic data to evaluate systemic exposure, either as an integral part of preclinical toxicity studies or in specifically designed supportive studies. This information helps in understanding the relationship between observed toxicity and the administered dose. Additionally, toxicokinetic assessment plays a crucial role in the clinical setting, aiding in the determination of plasma thresholds for early human exposure and in the estimation of safety margins.
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How To Cite (APA)
Ms. Jadhav Supriya Kailas, Mr. Kale Atulkumar Bajirao, Miss. Pooja Sudam Waje, Ms.Deore Sonika Balchand, & Mr. Aniket Dhulap (September-2024). Toxicokinetic evaluation in preclinical studies and applications of toxicokinetic. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(9), a50-a57. https://ijnrd.org/papers/IJNRD2409008.pdf
Issue
Volume 9 Issue 9, September-2024
Pages : a50-a57
Other Publication Details
Paper Reg. ID: IJNRD_300074
Published Paper Id: IJNRD2409008
Downloads: 000121987
Research Area: Pharmacy All
Country: Anjanvihire, MAHARASHTRA, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2409008.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2409008
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition


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