Effectiveness of a Superficial Chemical Peel with Kojic Acid, Lactic Acid, and Vitamin C for Treating Periorbital Hyperpigmentation

Registration ID: IJNRD_213533

Published ID: IJNRD2402068

DOI: http://doi.one/10.1729/Journal.37921

Dr. Vijayashree Mathad , Dr. Hansini Bhaskaran , Dr. Lavanya Alimeli

: Periorbital hyperpigmentation, Dark circles under eyes, Superficial chemical peel, Kojic acid, Lactic acid, Vitamin C

Introduction: Periorbital hyperpigmentation, also known as dark circles under the eyes, is a common aesthetic concern that affects many individuals. Several factors contribute to this condition, including genetics, aging, sun exposure, and lifestyle habits. Various treatments, such as topical creams, lasers, and chemical peels, have been proposed to address periorbital hyperpigmentation. This study aimed to investigate the efficacy and safety of a superficial chemical peel containing kojic acid, lactic acid, and vitamin C for treating periorbital hyperpigmentation. Methods: Twenty-five patients with periorbital hyperpigmentation were enrolled in this study from 2 centres in Karnataka and 1 centre from Hyderabad. The patients' ages ranged from 25 to 55 years, and they had mild to moderate hyperpigmentation. The patients received six weekly sessions of the chemical peel. The peel contained 5% kojic acid, 10% lactic acid, and 5% vitamin C. The patients were instructed to avoid sun exposure and use sunscreen during the study period. The patients' skin was evaluated before and after the treatment using a visual grading scale and a spectrophotometer. The patients' satisfaction with the treatment was also assessed. Results: The results showed significant improvement in hyperpigmentation, skin texture, and overall skin appearance after the treatment. The mean visual grading score decreased from 3.6 (SD=0.7) to 1.58 (SD=0.5), indicating a significant reduction in hyperpigmentation (p<0.001). The mean spectrophotometer reading decreased from 1.3 (SD=0.4) to 0.7 (SD=0.2), indicating a significant decrease in melanin content (p<0.001). The patients' satisfaction with the treatment was high, with 24 out of 25 patients reporting improvement in their skin. The peel was well-tolerated, with minimal side effects. The most common side effect was mild erythema, which resolved within 24 hours. No other adverse events were reported. Conclusion: This study demonstrated the efficacy and safety of a superficial chemical peel containing kojic acid, lactic acid, and vitamin C for treating periorbital hyperpigmentation. The peel resulted in significant improvement in hyperpigmentation, skin texture, and overall skin appearance, with high patient satisfaction and minimal side effects. These findings suggest that this peel could be a safe and effective treatment option for periorbital hyperpigmentation. Further studies with larger sample sizes and longer follow-up periods are needed to confirm these findings.

Published Paper   E-Certificate

Dr. Vijayashree Mathad, Dr. Hansini Bhaskaran, & Dr. Lavanya Alimeli (February-2024). Effectiveness of a Superficial Chemical Peel with Kojic Acid, Lactic Acid, and Vitamin C for Treating Periorbital Hyperpigmentation. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(2), a596-a601. http://doi.one/10.1729/Journal.37921

Volume 9 Issue 2, February-2024

Pages : a596-a601

Paper Reg. ID: IJNRD_213533

Published Paper Id: IJNRD2402068

Downloads: 000121990

Research Area: Health Science 

Country: Kalaburagi, karnataka, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2402068.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2402068

Crossref DOI: http://doi.one/10.1729/Journal.37921

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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