Effectiveness of a Superficial Chemical Peel with Kojic Acid, Lactic Acid, and Vitamin C for Treating Periorbital Hyperpigmentation

Effectiveness of a Superficial Chemical Peel with Kojic Acid, Lactic Acid, and Vitamin C for Treating Periorbital Hyperpigmentation

Registration ID: IJNRD_213533

Published ID: IJNRD2402068

DOI: http://doi.one/10.1729/Journal.37921

Dr. Vijayashree Mathad , Dr. Hansini Bhaskaran , Dr. Lavanya Alimeli

: Periorbital hyperpigmentation, Dark circles under eyes, Superficial chemical peel, Kojic acid, Lactic acid, Vitamin C

Introduction: Periorbital hyperpigmentation, also known as dark circles under the eyes, is a common aesthetic concern that affects many individuals. Several factors contribute to this condition, including genetics, aging, sun exposure, and lifestyle habits. Various treatments, such as topical creams, lasers, and chemical peels, have been proposed to address periorbital hyperpigmentation. This study aimed to investigate the efficacy and safety of a superficial chemical peel containing kojic acid, lactic acid, and vitamin C for treating periorbital hyperpigmentation. Methods: Twenty-five patients with periorbital hyperpigmentation were enrolled in this study from 2 centres in Karnataka and 1 centre from Hyderabad. The patients' ages ranged from 25 to 55 years, and they had mild to moderate hyperpigmentation. The patients received six weekly sessions of the chemical peel. The peel contained 5% kojic acid, 10% lactic acid, and 5% vitamin C. The patients were instructed to avoid sun exposure and use sunscreen during the study period. The patients' skin was evaluated before and after the treatment using a visual grading scale and a spectrophotometer. The patients' satisfaction with the treatment was also assessed. Results: The results showed significant improvement in hyperpigmentation, skin texture, and overall skin appearance after the treatment. The mean visual grading score decreased from 3.6 (SD=0.7) to 1.58 (SD=0.5), indicating a significant reduction in hyperpigmentation (p<0.001). The mean spectrophotometer reading decreased from 1.3 (SD=0.4) to 0.7 (SD=0.2), indicating a significant decrease in melanin content (p<0.001). The patients' satisfaction with the treatment was high, with 24 out of 25 patients reporting improvement in their skin. The peel was well-tolerated, with minimal side effects. The most common side effect was mild erythema, which resolved within 24 hours. No other adverse events were reported. Conclusion: This study demonstrated the efficacy and safety of a superficial chemical peel containing kojic acid, lactic acid, and vitamin C for treating periorbital hyperpigmentation. The peel resulted in significant improvement in hyperpigmentation, skin texture, and overall skin appearance, with high patient satisfaction and minimal side effects. These findings suggest that this peel could be a safe and effective treatment option for periorbital hyperpigmentation. Further studies with larger sample sizes and longer follow-up periods are needed to confirm these findings.

Published Paper   E-Certificate

"Effectiveness of a Superficial Chemical Peel with Kojic Acid, Lactic Acid, and Vitamin C for Treating Periorbital Hyperpigmentation", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 2, page no.a596-a601, February-2024, Available :https://ijnrd.org/papers/IJNRD2402068.pdf

Volume 9 Issue 2, February-2024

Pages : a596-a601

Paper Reg. ID: IJNRD_213533

Published Paper Id: IJNRD2402068

Downloads: 000121174

Research Area: Health Science 

Country: Kalaburagi, karnataka, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2402068.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2402068

DOI: http://doi.one/10.1729/Journal.37921

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

Call For Paper - Volume 10 | Issue 8 | August 2025

IJNRD is Scholarly open access journals, Peer-reviewed, and Refereed Journals, High Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool), Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) with Open-Access Publications.

INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world. IJNRD will provide an opportunity for practitioners and educators of engineering field to exchange research evidence, models of best practice and innovative ideas.

Indexing In Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar | AI-Powered Research Tool, Microsoft Academic, Academia.edu, arXiv.org, Research Gate, CiteSeerX, ResearcherID Thomson Reuters, Mendeley : reference manager, DocStoc, ISSUU, Scribd, and many more

How to submit the paper?

Important Dates for Current issue

Paper Submission Open For: August 2025

Current Issue: Volume 10 | Issue 8

Last Date for Paper Submission: Till 31-Aug-2025

Notification of Review Result: Within 1-2 Days after Submitting paper.

Publication of Paper: Within 01-02 Days after Submititng documents.

Frequency: Monthly (12 issue Annually).

Journal Type: International Peer-reviewed, Refereed, and Open Access Journal.

Subject Category: Research Area