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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Piperidine Unveiled: A Comprehensive Exploration of Structure, Applications, and Pharmacological Significance |
| Authors Name: | M.Reddemma , Ganga Supraja.K , Indhu priya , Harika , Mayuri.P |
| Download E-Certificate: | Download |
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IJNRD_213393
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| Published Paper Id: | IJNRD2402051 |
| Published In: | Volume 9 Issue 2, February-2024 |
| DOI: | |
| Abstract: | This review explores piperidine, an organic compound known for its molecular formula [CH2]5NH and unique six-membered ring structure. Piperidine is widely used in pharmaceuticals and alkaloids such as solenopsins. It is a colorless liquid with an amine odor and its name comes from the Latin word "piper," meaning pepper. The document covers its chemical properties, manufacturing processes, and applications in pharmaceuticals, rubber synthesis, corrosion inhibition, and catalysis.Piperidine and its derivatives have significant roles in insect repellents, hair loss prevention, antipsychotic medications, and opioids. It occurs naturally in black pepper and various plants. Derivatives like N-formyl piperidine are used as solvents and bases in various chemical processes. The review highlights the complex structures of piperidine and focuses on the mechanisms of action, particularly the anti-inflammatory and anti-tumor properties of the bioactive alkaloid evodiamine. The pharmacological spectrum of piperidine derivatives includes anti-diabetic, anti-cancer, anti-microbial, anti-inflammatory, anti-Alzheimer, anti-viral, anti-fungal, anti-hypertension, anti-malarial, and analgesic effects. Specific applications include voglibose for anti-diabetic properties and donepezil for Alzheimer's therapy. Insights extend to applications in anti-cancer chemotherapy, analgesics, anti-influenza agents, anti-tuberculosis medications, and anticoagulants. The review emphasizes the multifaceted role of piperidine and its derivatives, highlighting their ongoing significance in research and development. |
| Keywords: | Piperidine, chemical properties, piperidine derivatives, MOAs, and pharmacological actions. |
| Cite Article: | "Piperidine Unveiled: A Comprehensive Exploration of Structure, Applications, and Pharmacological Significance", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 2, page no.a473-a483, February-2024, Available :http://www.ijnrd.org/papers/IJNRD2402051.pdf |
| Downloads: | 000118759 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2402051 Registration ID: 213393 Published In: Volume 9 Issue 2, February-2024 DOI (Digital Object Identifier): Page No: a473-a483 Country: Tirupathi, Andhra Pradesh, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2402051 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2402051 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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