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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | PROBIOTICS POTENTIAL: EXPLORING THE GUT-BRAIN-AXIS IN CENTRAL NERVOUS SYSTEM |
| Authors Name: | VAISHNAVI SURAJ PATIL , SIDDHI VIVEK KHARE , JEEVISHA SANDIP SATPUTE , DIVYA GULAB CHANDRA MAURYA , KRUTIKA ARUN MORE |
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IJNRD_210964
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| Published Paper Id: | IJNRD2312151 |
| Published In: | Volume 8 Issue 12, December-2023 |
| DOI: | |
| Abstract: | Abstract; Probiotics are described as live microorganisms that benefit the host by enhancing its intestinal microbial composition. Studies have suggested a possible link between the digestive system and mental health. The moniker "Gut-Brain Axis" has been applied to this link. Probiotics known as "psych-biotics" work with commensal gut bacteria to provide mental health advantages to the host when consumed in specific amounts. According to the study, the bacteria found in probiotics stimulate the immune system or enteric nervous system by 1) Acting on the hypothalamus-pituitary axis, 2) Directly affecting the immune system, and 3) Secreting neurotransmitters. The brain may also modify intestinal permeability, which permits probiotic bacteria to pass through the epithelium and trigger an immune response in the mucosa, influencing the makeup and function of the microbiota. They can be applied to several neurological conditions, including autism, Parkinson's disease, Alzheimer's disease, multiple sclerosis, and Huntington's disease. The degenerative mechanisms of neurons, which are triggered by a variety of cytotoxic chemicals such as cytokines, exotoxins, reactive oxygen species, and many more, resulting in a variety of neurological diseases or disorders. The primary cause of these inflammatory mediators is an imbalance in the gut flora. Probiotic administration aids in their balance and produces short-chain fatty acids, propionates, and butyrates—all of which are created when non-digestible carbohydrates are fermented by bacteria. These substances are recognized to have beneficial effects on neurological health, and sufficient clinical data from researchers has been presented; this has been covered in the subsequent review article. |
| Keywords: | Probiotics, Psych-biotics, Gut-Brain – Axis, Neurodegenerative diseases, Microbiota |
| Cite Article: | "PROBIOTICS POTENTIAL: EXPLORING THE GUT-BRAIN-AXIS IN CENTRAL NERVOUS SYSTEM", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 12, page no.b307-b314, December-2023, Available :http://www.ijnrd.org/papers/IJNRD2312151.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2312151 Registration ID: 210964 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: b307-b314 Country: NASHIK, MAHARASHTRA, India Research Area: Medical Science Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2312151 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2312151 |
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ISSN: 2456-4184
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