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Paper Title

PROBIOTICS POTENTIAL: EXPLORING THE GUT-BRAIN-AXIS IN CENTRAL NERVOUS SYSTEM

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Registration ID: IJNRD_210964

Published ID: IJNRD2312151

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Keywords

Probiotics, Psych-biotics, Gut-Brain – Axis, Neurodegenerative diseases, Microbiota

Abstract

Abstract; Probiotics are described as live microorganisms that benefit the host by enhancing its intestinal microbial composition. Studies have suggested a possible link between the digestive system and mental health. The moniker "Gut-Brain Axis" has been applied to this link. Probiotics known as "psych-biotics" work with commensal gut bacteria to provide mental health advantages to the host when consumed in specific amounts. According to the study, the bacteria found in probiotics stimulate the immune system or enteric nervous system by 1) Acting on the hypothalamus-pituitary axis, 2) Directly affecting the immune system, and 3) Secreting neurotransmitters. The brain may also modify intestinal permeability, which permits probiotic bacteria to pass through the epithelium and trigger an immune response in the mucosa, influencing the makeup and function of the microbiota. They can be applied to several neurological conditions, including autism, Parkinson's disease, Alzheimer's disease, multiple sclerosis, and Huntington's disease. The degenerative mechanisms of neurons, which are triggered by a variety of cytotoxic chemicals such as cytokines, exotoxins, reactive oxygen species, and many more, resulting in a variety of neurological diseases or disorders. The primary cause of these inflammatory mediators is an imbalance in the gut flora. Probiotic administration aids in their balance and produces short-chain fatty acids, propionates, and butyrates—all of which are created when non-digestible carbohydrates are fermented by bacteria. These substances are recognized to have beneficial effects on neurological health, and sufficient clinical data from researchers has been presented; this has been covered in the subsequent review article.

How To Cite (APA)

VAISHNAVI SURAJ PATIL, SIDDHI VIVEK KHARE, JEEVISHA SANDIP SATPUTE, DIVYA GULAB CHANDRA MAURYA, & KRUTIKA ARUN MORE (December-2023). PROBIOTICS POTENTIAL: EXPLORING THE GUT-BRAIN-AXIS IN CENTRAL NERVOUS SYSTEM. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(12), b307-b314. https://ijnrd.org/papers/IJNRD2312151.pdf

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Other Publication Details

Paper Reg. ID: IJNRD_210964

Published Paper Id: IJNRD2312151

Research Area: Medical Science

Author Type: Indian Author

Country: NASHIK, MAHARASHTRA, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2312151.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2312151

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