INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Most topical formulations are intended for skin application. For convenience of storage and requiring an applicator or the use of a fingertip to apply, the topical medication delivery methods have several drawbacks that could cause contamination. Therefore, it was imperative to find a solution to effectively combat all the drawbacks, The objective of this study is to develop innovative drug delivery system to cure topical fungal infection such as superficial mycosis. The incidence of superficial fungal infections of skin, hairs, and nails has been increased worldwide. Itraconazole has anti-fungal activity. For the formulation of 1% Itraconazole medistick, self-emulsifying drug delivery system (SEDDS) was prepared using appropriate oil, surfactants, and co-surfactants to improve solubility, penetration, and bioavailability. The microemulsion was then incorporated into the lipstick base containing appropriate amount of wax, lanoline, castor oil, cetyl alcohol, preservative, antioxidant, and perfume to prepare medicated lipstick. Results of evaluation tests like pH, breaking load, softening point, melting point, rancidity, etc. confirmed required physicochemical properties of formulated medistick. Overall, the findings of this research work imply that itraconazole medistick is a good patient friendly alternative to existing treatment of superficial mycosis.
"NOVEL MEDISTICK FORMULATION OF ITRACONAZOLE FOR TREATMENT OF SUPERFICIAL MYCOSIS", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 9, page no.c460-c467, September-2023, Available :http://www.ijnrd.org/papers/IJNRD2309252.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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