Paper Title
NOVEL MEDISTICK FORMULATION OF ITRACONAZOLE FOR TREATMENT OF SUPERFICIAL MYCOSIS
Article Identifiers
Authors
SARIKA R.KALE , MONITA P. GIDE , APURVA S. BELSARKAR , ANKITA JORVEKAR
Keywords
Itraconazole; Medicated stick; SEDDS; Superficial Mycosis
Abstract
Most topical formulations are intended for skin application. For convenience of storage and requiring an applicator or the use of a fingertip to apply, the topical medication delivery methods have several drawbacks that could cause contamination. Therefore, it was imperative to find a solution to effectively combat all the drawbacks, The objective of this study is to develop innovative drug delivery system to cure topical fungal infection such as superficial mycosis. The incidence of superficial fungal infections of skin, hairs, and nails has been increased worldwide. Itraconazole has anti-fungal activity. For the formulation of 1% Itraconazole medistick, self-emulsifying drug delivery system (SEDDS) was prepared using appropriate oil, surfactants, and co-surfactants to improve solubility, penetration, and bioavailability. The microemulsion was then incorporated into the lipstick base containing appropriate amount of wax, lanoline, castor oil, cetyl alcohol, preservative, antioxidant, and perfume to prepare medicated lipstick. Results of evaluation tests like pH, breaking load, softening point, melting point, rancidity, etc. confirmed required physicochemical properties of formulated medistick. Overall, the findings of this research work imply that itraconazole medistick is a good patient friendly alternative to existing treatment of superficial mycosis.
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How To Cite (APA)
SARIKA R.KALE, MONITA P. GIDE, APURVA S. BELSARKAR, & ANKITA JORVEKAR (September-2023). NOVEL MEDISTICK FORMULATION OF ITRACONAZOLE FOR TREATMENT OF SUPERFICIAL MYCOSIS. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(9), c460-c467. https://ijnrd.org/papers/IJNRD2309252.pdf
Issue
Volume 8 Issue 9, September-2023
Pages : c460-c467
Other Publication Details
Paper Reg. ID: IJNRD_205526
Published Paper Id: IJNRD2309252
Downloads: 000122003
Research Area: Pharmacy
Country: TNANE MUMBAI, MAHARASHTRA, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2309252.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2309252
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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IJNRD is a Scholarly Open Access, Peer-reviewed, and Refereed Journal with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost Journal that follows UGC CARE 2025 Peer-Reviewed Journal Policy norms, Scopus journal standards, and Transparent Peer Review practices to ensure quality and credibility. IJNRD provides indexing in all major databases & metadata repositories, a citation generator, and Digital Object Identifier (DOI) for every published article with full open-access visibility.
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