Paper Title
DETAILED DRUG INFORMATION OF ADO TRASTUZUMAB EMTANSINE AND ITS THERAPEUTIC USES.
Article Identifiers
Authors
Vedant Sheth , Akansha Pandit , Honey Desai , Dhaval Chauhan , SP Srinivas Nayak
Keywords
T-DM1, HER2-positive breast cancer, targeted treatment, combination therapy,clinical evidence,trastuzumab-emtansine.
Abstract
Ado trastuzumab emtansine, a medication used to treat breast cancer that is HER2-positive, is discussed in great detail in this review article. Ado-trastuzumab emtansine, sometimes referred to as T-DM1, is an amalgamation of the cytotoxic DM1 medication and the anti-HER2 medicine trastuzumab. This medication works by delivering DM1 to cancer cells via attaching on the HER 2 receptor on cancer cells. Cell cycle interruption and death of cells (apoptosis) are the results of this. It has been demonstrated that ado-trastuzumab emtansine is successful in treating HER 2-positive, early-stage breast cancer. But it can also result in negative side effects like discomfort, exhaustion, and even heart damage. This medication is administered intravenously and is metabolised in the liver. It has a half-life of roughly 70 hours and is eliminated through the urine and stool.Ado trastuzumab emtansine may interact with other medications and may require dose adjustment. In general, this is a good way to treat HER2-positive breast cancer.
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How To Cite (APA)
Vedant Sheth, Akansha Pandit, Honey Desai, Dhaval Chauhan , & SP Srinivas Nayak (September-2023). DETAILED DRUG INFORMATION OF ADO TRASTUZUMAB EMTANSINE AND ITS THERAPEUTIC USES.. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(9), b855-b861. https://ijnrd.org/papers/IJNRD2309198.pdf
Issue
Volume 8 Issue 9, September-2023
Pages : b855-b861
Other Publication Details
Paper Reg. ID: IJNRD_205434
Published Paper Id: IJNRD2309198
Downloads: 000121981
Research Area: Pharmacy
Country: Vadodara, Gujarat, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2309198.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2309198
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