Cr(NO3)3•9H2O: An efficient, eco-friendly, economical and non-toxic catalyst, as well as the solvent-free conditions for biological applications

Cr(NO3)3•9H2O: An efficient, eco-friendly, economical and non-toxic catalyst, as well as the solvent-free conditions for biological applications

Registration ID: IJNRD_205265

Published ID: IJNRD2309197

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Dr S Thenmozhi , Dr S R Chitra , Mrs D Sudha , Mr S S Saravanakumar

Chromium (III) nitrate nonahydrate; heterogeneous catalyst; non-toxic catalyst; Solvent-free conditions; Biginelli synthesis

The development of chromium (III) nitrate nonahydrate (Cr(NO3)3•9H2O) as well-organized, soft and an inexpensive catalyst for Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives in the reaction between β-keto esters (methyl or ethyl acetoacetate), aromatic aldehydes (benzaldehye derivatives) and urea or thiourea beneath thermal and solvent-free conditions with good yields and short reaction times is reported. The majority reimbursement of this synthetic method contains the use of an efficient, eco-friendly, inexpensive and non-toxic catalyst, as well as the solvent-free conditions. All products were characterized by 1H NMR spectroscopy and melting point determination.

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"Cr(NO3)3•9H2O: An efficient, eco-friendly, economical and non-toxic catalyst, as well as the solvent-free conditions for biological applications", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 9, page no.b843-b854, September-2023, Available :https://ijnrd.org/papers/IJNRD2309197.pdf

Volume 8 Issue 9, September-2023

Pages : b843-b854

Paper Reg. ID: IJNRD_205265

Published Paper Id: IJNRD2309197

Downloads: 000121156

Research Area: Science & Technology

Country: MADURAI, TAMILNADU, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2309197.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2309197

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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