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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Preparation And Evaluation of Fast Dissolving Tablets of Atenolol With Combination of Different Concentrations of Superdisintegrants By Direct Compression Technique |
| Authors Name: | Lakshmi Radhika G , Chandan NJ , Aroodha V Maragur , Lalu Gowda V |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_205038
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| Published Paper Id: | IJNRD2309073 |
| Published In: | Volume 8 Issue 9, September-2023 |
| DOI: | |
| Abstract: | The purpose of this research was to formulate fast dissolving tablets (FDT) In the present work efforts have been made to prepare and evaluate fast dissolving tablets of atenolol with combination of different concentrations of superdisintegrants crospovidone, sodium starch glycolate by direct compression technique. fast dissolving tablets are designed to disintegrate and dissolve in saliva and then easily swallowed without need of water which is a major benefit over conventional dosage form. Atenolol, a β1-blocker, is prescribed widely in diverse cardiovascular diseases, eg, hypertension, angina pectoris, arrhythmias, and myocardial infarction. preparation and evaluation preparation of atenolol fast dissolving tablet with combination of different concentrations of superdisintegrants crospovidone, sodium starch glycolate by direct compression technique. The results revealed that the increased proportion of various superdisintegrants were associated with increase in the overall cumulative drug release rate. The developed tablets were evaluated for hardness, friability, drug content, weight variation, uniformity of dispersion, wetting time, wetting volume, in vitro dispersion time, in vitro disintegration time and in vitro drug release. The dissolution profiles of prepared tablets were compared with pure drug and marketed product. Rapid disintegration of tablets formulated in this research possibly help in administration |
| Keywords: | Atenolol, fast dissolving Tablets (FDTs), Superdisintegrants |
| Cite Article: | "Preparation And Evaluation of Fast Dissolving Tablets of Atenolol With Combination of Different Concentrations of Superdisintegrants By Direct Compression Technique", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 9, page no.a600-a610, September-2023, Available :http://www.ijnrd.org/papers/IJNRD2309073.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2309073 Registration ID: 205038 Published In: Volume 8 Issue 9, September-2023 DOI (Digital Object Identifier): Page No: a600-a610 Country: -, -, India Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2309073 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2309073 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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