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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | DIFFERENT TYPES OF ANTI-DIABETIC DRUG EFFECT ON PATIENT OF-TYPE 2 DIABETES MELLITUS |
| Authors Name: | ARPITA SARKAR |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_204329
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| Published Paper Id: | IJNRD2308346 |
| Published In: | Volume 8 Issue 8, August-2023 |
| DOI: | |
| Abstract: | Diabetes mellitus (DM) is a metabolic disorder that occurs in the body because of decreased insulin activity and/or insulin secretion. Pathological changes such as nephropathy, retinopathy and cardiovascular complications inevitably occur in the body with the progression of the disease. DM is mainly categorized into 2 sub-types, type 1 DM and type 2 DM. While type 1 DM is generally treated through insulin replacement therapy, type 2 DM is treated with oral hypoglycaemia. The major drug therapy for type 2 DM comprises of insulin secretagogues, biguanides, insulin sensitizers, alpha glucosidase inhibitors, incretin mimetics, amylin antagonists and sodium-glucose co-transporter-2 (SGLT2) inhibitors. Dual drug therapies are often recommended in patients who are unable to achieve therapeutic goals with first line oral hypoglycemic agents as monotherapy. In spite of the appreciable therapeutic benefits, the conventional dosage forms depict differential bioavailability and short Half-life, mandating frequent dosage and causing greater side effects leading to therapy ineffectiveness and patient non-compliance. Given the pathological complexity of the said disease, nanotechnology-based approaches are more enticing as it comes with added advantage of site-specific drug delivery with higher bioavailability and reduced dosage regimen. |
| Keywords: | Type 2 Diabetes mellitus, Monotherapy, Combination therapy, Novel drug delivery system. |
| Cite Article: | "DIFFERENT TYPES OF ANTI-DIABETIC DRUG EFFECT ON PATIENT OF-TYPE 2 DIABETES MELLITUS", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 8, page no.d270-d277, August-2023, Available :http://www.ijnrd.org/papers/IJNRD2308346.pdf |
| Downloads: | 000118749 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2308346 Registration ID: 204329 Published In: Volume 8 Issue 8, August-2023 DOI (Digital Object Identifier): Page No: d270-d277 Country: Kolkata, West Bengal, India Research Area: Life Sciences Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2308346 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2308346 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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