Paper Title
DIFFERENT TYPES OF ANTI-DIABETIC DRUG EFFECT ON PATIENT OF-TYPE 2 DIABETES MELLITUS
Article Identifiers
Authors
ARPITA SARKAR
Keywords
Type 2 Diabetes mellitus, Monotherapy, Combination therapy, Novel drug delivery system.
Abstract
Diabetes mellitus (DM) is a metabolic disorder that occurs in the body because of decreased insulin activity and/or insulin secretion. Pathological changes such as nephropathy, retinopathy and cardiovascular complications inevitably occur in the body with the progression of the disease. DM is mainly categorized into 2 sub-types, type 1 DM and type 2 DM. While type 1 DM is generally treated through insulin replacement therapy, type 2 DM is treated with oral hypoglycaemia. The major drug therapy for type 2 DM comprises of insulin secretagogues, biguanides, insulin sensitizers, alpha glucosidase inhibitors, incretin mimetics, amylin antagonists and sodium-glucose co-transporter-2 (SGLT2) inhibitors. Dual drug therapies are often recommended in patients who are unable to achieve therapeutic goals with first line oral hypoglycemic agents as monotherapy. In spite of the appreciable therapeutic benefits, the conventional dosage forms depict differential bioavailability and short Half-life, mandating frequent dosage and causing greater side effects leading to therapy ineffectiveness and patient non-compliance. Given the pathological complexity of the said disease, nanotechnology-based approaches are more enticing as it comes with added advantage of site-specific drug delivery with higher bioavailability and reduced dosage regimen.
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How To Cite (APA)
ARPITA SARKAR (August-2023). DIFFERENT TYPES OF ANTI-DIABETIC DRUG EFFECT ON PATIENT OF-TYPE 2 DIABETES MELLITUS. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(8), d270-d277. https://ijnrd.org/papers/IJNRD2308346.pdf
Issue
Volume 8 Issue 8, August-2023
Pages : d270-d277
Other Publication Details
Paper Reg. ID: IJNRD_204329
Published Paper Id: IJNRD2308346
Downloads: 000121976
Research Area: Life SciencesÂ
Country: Kolkata, West Bengal, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2308346.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2308346
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