Inflammasomes: Promising Targets In Therapeutic Strategies For Covid 19

Registration ID: IJNRD_204114

Published ID: IJNRD2308266

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Omkar Deshmukh , Smita Nayak , Vaidhun Bhaskar

NLRP3 inflammasomes, Anakinra, Lipoxin, Cytokines, Ginseng.

Clinical symptoms caused by SARS-CoV-2, the virus that was responsible for the spread of COVID-19, vary from no symptoms to severe pneumonia and death. Several studies point to the critical role of inflammatory cytokines in initiating and exacerbating the immune response, leading to the overproduction of cytokines as well as chemokines and ultimately resulting in a cytokine storm. A significant contributing factor to the uncontrolled pro-inflammatory response to the viral infection is the activation of the NLRP3 inflammasome, a part of the innate immune system. For the creation of therapeutic approaches to treat COVID-19, this inflammasome can be employed as a target. The NLRP3 inflammasome's structure is described in this review, along with the many methods that have been used to target it.

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Omkar Deshmukh, Smita Nayak, & Vaidhun Bhaskar (August-2023). Inflammasomes: Promising Targets In Therapeutic Strategies For Covid 19. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(8), c497-c502. https://ijnrd.org/papers/IJNRD2308266.pdf

Volume 8 Issue 8, August-2023

Pages : c497-c502

Paper Reg. ID: IJNRD_204114

Published Paper Id: IJNRD2308266

Downloads: 000121974

Research Area: Health Science 

Country: Navi Mumbai, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2308266.pdf

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