INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
: Artemisinin’s are widely known for treating malaria, even in extremely drug-resistant forms, and are extracted from extracts of sweet wormwood (Artemisia annua). Their effectiveness also covers parasitic illnesses with different evolutionary relationships, like schistosomiasis. In cell lines and animal models more recently, they have also demonstrated strong and extensive anticancer activities. We explore recent developments in identifying the function of artemisinins in medicine in this review. with a focus on their debatable methods of action in particular. This affordable medication class that prevents malaria and saves lives also has significant potential in on cology. One of the most often prescribed antimalarial medications, artemisinin has recently drawn more attention due to other potential biological effects. This review's objective is to describe recent advancements in basic science on artemisinin's pharmacological effects, as well as its molecular action and exciting clinical study findings, with an emphasis on its anticancer activity. According to scientific data, the biological activity of artemisinin is mediated through the production of reactive oxygen species (ROS), which cause DNA damage, mitochondrial depolarization, and cell death. The scientific evidence presented in this article review points to artemisinin as a potential treatment agent for a number of disorders. Therefore, this analysis is anticipated to inspire interested researchers to carry out more preclinical and clinical investigations to assess these biological activities.
Keywords:
Chemishtry And Synthesis,Metabolism And Pharmacokinetics,Antimalarial Properties.
Cite Article:
": To Review On Pharmacological Action On Artemisinin ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 4, page no.e120-e127, April-2023, Available :http://www.ijnrd.org/papers/IJNRD2304419.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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