Paper Title
A REVIEW ON RECENT ADVANCES IN TRANSDERMAL DRUG DELIVERY SYSTEM
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Registration ID: IJNRD_191024
Published ID: IJNRD2304207
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Keywords
Transdermal drug delivery, Skin penetration enhancer, Stratum corneum, Iontophoresis, Sonophoresis.
Abstract
Transdermal drug delivery offers an attractive alternative to the conventional drug delivery methods of oral administration and injection.The delivery of drugs into systemic circulation via skin has generated much attention during the last decade. Drugs administered through these systems escape first-pass metabolism and maintain a steady state scenario similar to a continuous intravenous infusion for up to several days. However, the stratum corneum acts as a barrier that limits the penetration of substances through the skin. Different approaches of penetration enhancement are used such as Ultrasound (sonophoresis) and Iontophoresis are both promising technologies.The rationale behind using this technique is to reversibly alter the barrier properties of skin, which could possibly improve the penetration of drugs such as proteins, peptides and other macromolecules to increase the systemic delivery of high molecular weight compounds with controlled input kinetics and minimum inter-subject variability. Transdermal biology delivery, as well as standard drugs, is becoming increasingly popular as the method provides countless benefits. It decreases pain, biohazardous waste and infection danger. Mostly, needle-free drug delivery generally increases patient compliance. The review presents mainly the routes of penetration through skin and the physical approach of penetration enhancement to optimise the transdermal delivery system and future trends in the field of cutaneous vaccination and gene delivery.
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How To Cite (APA)
Nandini S. Burshe & Mr. Pramod M. Bhosale (April-2023). A REVIEW ON RECENT ADVANCES IN TRANSDERMAL DRUG DELIVERY SYSTEM. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(4), c47-c55. https://ijnrd.org/papers/IJNRD2304207.pdf
Issue
Volume 8 Issue 4, April-2023
Pages : c47-c55
Other Publication Details
Paper Reg. ID: IJNRD_191024
Published Paper Id: IJNRD2304207
Research Area: Pharmacy
Author Type: Indian Author
Country: Jalna, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2304207.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2304207
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