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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | A REVIEW ON RECENT ADVANCES IN TRANSDERMAL DRUG DELIVERY SYSTEM |
| Authors Name: | Nandini S. Burshe , Mr. Pramod M. Bhosale |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_191024
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| Published Paper Id: | IJNRD2304207 |
| Published In: | Volume 8 Issue 4, April-2023 |
| DOI: | |
| Abstract: | Transdermal drug delivery offers an attractive alternative to the conventional drug delivery methods of oral administration and injection.The delivery of drugs into systemic circulation via skin has generated much attention during the last decade. Drugs administered through these systems escape first-pass metabolism and maintain a steady state scenario similar to a continuous intravenous infusion for up to several days. However, the stratum corneum acts as a barrier that limits the penetration of substances through the skin. Different approaches of penetration enhancement are used such as Ultrasound (sonophoresis) and Iontophoresis are both promising technologies.The rationale behind using this technique is to reversibly alter the barrier properties of skin, which could possibly improve the penetration of drugs such as proteins, peptides and other macromolecules to increase the systemic delivery of high molecular weight compounds with controlled input kinetics and minimum inter-subject variability. Transdermal biology delivery, as well as standard drugs, is becoming increasingly popular as the method provides countless benefits. It decreases pain, biohazardous waste and infection danger. Mostly, needle-free drug delivery generally increases patient compliance. The review presents mainly the routes of penetration through skin and the physical approach of penetration enhancement to optimise the transdermal delivery system and future trends in the field of cutaneous vaccination and gene delivery. |
| Keywords: | Transdermal drug delivery, Skin penetration enhancer, Stratum corneum, Iontophoresis, Sonophoresis. |
| Cite Article: | "A REVIEW ON RECENT ADVANCES IN TRANSDERMAL DRUG DELIVERY SYSTEM", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 4, page no.c47-c55, April-2023, Available :http://www.ijnrd.org/papers/IJNRD2304207.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2304207 Registration ID: 191024 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): Page No: c47-c55 Country: Jalna, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2304207 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2304207 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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