The blood-brain barrier: an overview: mechanisms, functions, treatment & Clinical implications

Registration ID: IJNRD_190220

Published ID: IJNRD2304056

DOI: https://doi.org/10.5281/zenodo.7901862

Asiya Nisa , Swastika Jha , Priyanka

:- Treatment. Blood–brain barrier; CNS; Degenerative; Disruption; Integrity; Markers; Neuroinflammation; Permeability; TEER; Tight junctions; Transcytosis.

All of the body's tissues and organs depend on blood arteries to carry oxygen and nutrients to them. The blood-brain barrier, a special property of the blood arteries that vascularize the central nervous system (CNS), enables these vessels to tightly control the transit of ions, chemicals, and cells between the blood and the brain. Correct neuronal function is enabled by the careful regulation of CNS homeostasis, which also safeguards neural tissue from toxins and infections. Alterations to these barrier qualities play a significant role in the pathophysiology and development of various neurological illnesses. The endothelial cells (ECs), which make up the blood vessel walls, have a variety of physical, transport, and metabolic characteristics that help to coordinate the physiological barrier. The unique characteristics of the Blood-Brain Barrier must be taken into account in any programme for drug discovery or delivery that seeks to target or avoid the CNS.

Published Paper   E-Certificate

Asiya Nisa, Swastika Jha, & Priyanka (April-2023). The blood-brain barrier: an overview: mechanisms, functions, treatment & Clinical implications. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(4), a462-a472. https://doi.org/10.5281/zenodo.7901862

Volume 8 Issue 4, April-2023

Pages : a462-a472

Paper Reg. ID: IJNRD_190220

Published Paper Id: IJNRD2304056

Downloads: 000121978

Research Area: Science

Country: Bangalore, karnataka, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2304056.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2304056

Crossref DOI: https://doi.org/10.5281/zenodo.7901862

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave | IJNRD.ORG | IJNRD.COM | IJPUB.ORG

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

Call For Paper - Volume 10 | Issue 10 | October 2025

IJNRD is a Scholarly Open Access, Peer-reviewed, and Refereed Journal with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost Journal that follows UGC CARE 2025 Peer-Reviewed Journal Policy norms, Scopus journal standards, and Transparent Peer Review practices to ensure quality and credibility. IJNRD provides indexing in all major databases & metadata repositories, a citation generator, and Digital Object Identifier (DOI) for every published article with full open-access visibility.

The INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to advance applied, theoretical, and experimental research across diverse fields. Its goal is to promote global scientific information exchange among researchers, developers, engineers, academicians, and practitioners. IJNRD serves as a platform where educators and professionals can share research evidence, models of best practice, and innovative ideas, contributing to academic growth and industry relevance.

Indexing Coverage includes Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar (AI-Powered Research Tool), Microsoft Academic, Academia.edu, arXiv.org, ResearchGate, CiteSeerX, ResearcherID (Thomson Reuters), Mendeley, DocStoc, ISSUU, Scribd, and many more recognized academic repositories.

How to submit the paper?

Important Dates for Current issue

Paper Submission Open For: October 2025

Current Issue: Volume 10 | Issue 10 | October 2025

Impact Factor: 8.76

Last Date for Paper Submission: Till 31-Oct-2025

Notification of Review Result: Within 1-2 Days after Submitting paper.

Publication of Paper: Within 01-02 Days after Submititng documents.

Frequency: Monthly (12 issue Annually).

Journal Type: IJNRD is an International Peer-reviewed, Refereed, and Open Access Journal with Transparent Peer Review as per the new UGC CARE 2025 guidelines, offering low-cost multidisciplinary publication with Crossref DOI and global indexing.

Subject Category: Research Area

Call for Paper: More Details