A correlative study of mixed fungal infection with special emphasis on mucormycosis in covid-19 patients: An early diagnosis improves the patient outcome

A correlative study of mixed fungal infection with special emphasis on mucormycosis in covid-19 patients: An early diagnosis improves the patient outcome

Registration ID: IJNRD_187795

Published ID: IJNRD2302249

DOI: Click Here to Get

Saba Shakil

Mucormycosis, Covid-19, Pandemic, Mixed infection, Cytology

Background: Mucormycosis is rare but fatal angioinvasive fungal infection which require prompt diagnosis and treatment.These are opportunistic organisms that affect people who are immunocompromised or on some steroids/chemotherapy drugs. Methods: The present study was conducted on 48 clinically suspected cases of rhino-orbital mucormycosis. Patients were between 30-70 years and presented with complaints of pain and swelling in the rhino-orbital region.The samples were recieved in normal saline and crush/imprint smears were prepared and stained with H & E,PAP and PAS stains for rapid cytological evaluation and also correlated with histopathology. Results: Total of 48 specimens from patients with suspected mucormycosis were recieved in the department of pathology, JNMCH, Aligarh over a period of six months. On cytology, out of 48 suspected caseses, 21 cases (43.8%) were found to be positive for isolated mucormycosis. 2 cases of mixed infection were also reported,1 case each of mucor with candida (2%) and mucor with aspergillous (2%). 3 cases (6.3%) were reported as suspicious for mucormycosis and 22 cases (45.8%) were diagnosed as negative. On histopathological correlation, 39 cases (81.3%) were positive for mucormycosis and 9 cases (18.7%) were negative. Among 48 cases, 43 cases (89.6%) had history of covid infection/RTPCR positive for covid infection. Diabetes was most common co-morbid condition, present in 39cases (81.3%). Conclusions: Timely diagnosis and early detection by crush/imprint smear saves the time and early treatment on the same day of admission can be started for such a lethal and angioinvasive condition.

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"A correlative study of mixed fungal infection with special emphasis on mucormycosis in covid-19 patients: An early diagnosis improves the patient outcome", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 2, page no.c411-c419, February-2023, Available :https://ijnrd.org/papers/IJNRD2302249.pdf

Volume 8 Issue 2, February-2023

Pages : c411-c419

Paper Reg. ID: IJNRD_187795

Published Paper Id: IJNRD2302249

Downloads: 000121103

Research Area: Engineering

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Published Paper PDF: https://ijnrd.org/papers/IJNRD2302249.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2302249

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world. IJNRD will provide an opportunity for practitioners and educators of engineering field to exchange research evidence, models of best practice and innovative ideas.

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