A correlative study of mixed fungal infection with special emphasis on mucormycosis in covid-19 patients: An early diagnosis improves the patient outcome

Registration ID: IJNRD_187795

Published ID: IJNRD2302249

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Saba Shakil

Mucormycosis, Covid-19, Pandemic, Mixed infection, Cytology

Background: Mucormycosis is rare but fatal angioinvasive fungal infection which require prompt diagnosis and treatment.These are opportunistic organisms that affect people who are immunocompromised or on some steroids/chemotherapy drugs. Methods: The present study was conducted on 48 clinically suspected cases of rhino-orbital mucormycosis. Patients were between 30-70 years and presented with complaints of pain and swelling in the rhino-orbital region.The samples were recieved in normal saline and crush/imprint smears were prepared and stained with H & E,PAP and PAS stains for rapid cytological evaluation and also correlated with histopathology. Results: Total of 48 specimens from patients with suspected mucormycosis were recieved in the department of pathology, JNMCH, Aligarh over a period of six months. On cytology, out of 48 suspected caseses, 21 cases (43.8%) were found to be positive for isolated mucormycosis. 2 cases of mixed infection were also reported,1 case each of mucor with candida (2%) and mucor with aspergillous (2%). 3 cases (6.3%) were reported as suspicious for mucormycosis and 22 cases (45.8%) were diagnosed as negative. On histopathological correlation, 39 cases (81.3%) were positive for mucormycosis and 9 cases (18.7%) were negative. Among 48 cases, 43 cases (89.6%) had history of covid infection/RTPCR positive for covid infection. Diabetes was most common co-morbid condition, present in 39cases (81.3%). Conclusions: Timely diagnosis and early detection by crush/imprint smear saves the time and early treatment on the same day of admission can be started for such a lethal and angioinvasive condition.

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Saba Shakil (February-2023). A correlative study of mixed fungal infection with special emphasis on mucormycosis in covid-19 patients: An early diagnosis improves the patient outcome. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(2), c411-c419. https://ijnrd.org/papers/IJNRD2302249.pdf

Volume 8 Issue 2, February-2023

Pages : c411-c419

Paper Reg. ID: IJNRD_187795

Published Paper Id: IJNRD2302249

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Research Area: Engineering

Author Type: Foreign Author

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Published Paper PDF: https://ijnrd.org/papers/IJNRD2302249.pdf

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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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