In-Vitro cytotoxicity effect of RUELLIA BRITONIANA flower on cervical Hela cancer cells.

Registration ID: IJNRD_300483

Published ID: IJNRDTH00195

: Click Here to Get

Chaithra

phytochemical constituents, biological, Ruellia, Acanthaceae

Cancer can be defined very broadly as disease in which there is uncontrolled multiplication and spreadwith in the body of abnormal forms of the body’s own cells. Strictly speaking ,one should use the term ‘neoplasm’ (mean ing a new growth) rather than the ‘cancer’.Neoplasms which have only the characteristic of localized growth are classified as ‘benign’.Neoplasms with the add itional characteristics of invasiveness and/or the capacity to metastasis are classified as ‘malignant’.The term cancer is usually applied only to this later types of growth.The word ‘tumour’ though in reality meaning ‘a local swelling’is also often use dinter changeably with cancer and will be soused now adays. According to the World Health Organisation estimates, cancer, which caused an unprecedented 9.6 million deaths in 2018 or one in six, and worldwide the second leading cause of mortality. The current treatment approaches of cancer include surgical operations, radiation induced therapy, chemotherapy, immune modulation therapy, targeted approaches, hormonal treatment, stem cell transplantation and precision medicine. Medicinal plants and their derivatives are widely accepted as effective alternative cancer therapies. A large number of clinical trials documented the effects of herbal medicinal products for cancer patients in conjunction with traditional therapeutics on recovery, immune modulation and quality of life. Ruellia is a genus of flowering plants commonly known as Ruellias or Wild Petunias which belongs to the family Acanthaceae. It contains about 250 genera and 2500 species. Most of these are shrubs, or twining vines; some are epiphytes. Only a few species are distributed in temperate regions. They are distributed in Indonesia and Malaysia, Africa, Brazil, Central America and Pakistan. Some of these are used as medicinal plants. Many species of the genus has antinociceptive, antioxidant, analgesic, antispasmolytic, antiulcer, antidiabetic and anti-inflammatory properties. The phytochemicals constituents: glycosides, alkaloids, flavonoids and triterpenoids have been found to be present in it. The genus has been traditionally claimed to be used for the treatment of flu, asthma, fever, bronchitis, high blood pressure, eczema, and diabetes. The objective of this research work was to understand the pharmacological and phytochemical aspects of this drug and to further find the gaps in research and endorse this genus as a step towards becoming a commercial drug. Hence, further work required is to isolate and characterize the active compounds responsible for these activities in this plant and bring this genus plants to commercial health market to serve the community with their potential benefits.

Published Paper   E-Certificate

Chaithra (September-2024). In-Vitro cytotoxicity effect of RUELLIA BRITONIANA flower on cervical Hela cancer cells.. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(9), 792-853. https://ijnrd.org/papers/IJNRDTH00195.pdf

Volume 9 Issue 9, September-2024

Pages : 792-853

Paper Reg. ID: IJNRD_300483

Published Paper Id: IJNRDTH00195

Downloads: 000122002

Research Area: Pharmacy All

Author Type: Indian Author

Country: bangalore, karnataka, India

Published Paper PDF: https://ijnrd.org/papers/IJNRDTH00195.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRDTH00195

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

UGC CARE JOURNAL PUBLICATION | ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave | IJNRD.ORG | IJNRD.COM | IJPUB.ORG

© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License. and The Open Definition.

You are free to share, adapt, and redistribute the material, provided proper credit is given to the original author. 🛡️ Disclaimer: The content, data, and findings in this article are based on the authors’ research and have been peer-reviewed for academic purposes only. Readers are advised to verify all information before practical or commercial use. The journal and its editorial board are not liable for any errors, losses, or consequences arising from its use.

Call For Paper - Volume 10 | Issue 11 | November 2025

IJNRD is a Scholarly Open Access, Peer-Reviewed, Refereed, and UGC CARE Journal Publication with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost, and Transparent Peer Review Journal Publication that adheres to the UGC CARE 2025 Peer-Reviewed Journal Policy and aligns with Scopus Journal Publication standards to ensure the highest level of research quality and credibility.

IJNRD offers comprehensive Journal Publication Services including indexing in all major databases and metadata repositories, Digital Object Identifier (Crossref DOI) assignment for each published article with additional fees, citation generation tools, and full Open Access visibility to enhance global research reach and citation impact.

The INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to advance applied, theoretical, and experimental research across diverse academic and professional fields. The journal promotes global knowledge exchange among researchers, developers, academicians, engineers, and practitioners, serving as a trusted platform for innovative, peer-reviewed journal publication and scientific collaboration.

Indexing Coverage: Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar (AI-Powered Research Tool), Microsoft Academic, Academia.edu, arXiv.org, ResearchGate, CiteSeerX, ResearcherID (Thomson Reuters), Mendeley, DocStoc, ISSUU, Scribd, and many other recognized academic repositories.

How to submit the paper?

By Our website

Click Here to Submit Paper Online

By Mail

Send your paper to editor@ijnrd.org

You can now publish your research in IJNRD. IJNRD is a Transparent Peer-Reviewed Open Access Journal Publication (Refereed Journal), aligning with New UGC and UGC CARE recommendations.

For more details, refer to the official notice: UGC Public Notice

Submit Paper Online

Important Dates for Current issue

Paper Submission Open For: November 2025

Current Issue: Volume 10 | Issue 11 | November 2025

Impact Factor: 8.76

Last Date for Paper Submission: Till 30-Nov-2025

Notification of Review Result: Within 1-2 Days after Submitting paper.

Publication of Paper: Within 01-02 Days after Submititng documents.

Frequency: Monthly (12 issue Annually).

Journal Type: IJNRD is an International Peer-reviewed, Refereed, and Open Access Journal with Transparent Peer Review as per the new UGC CARE 2025 guidelines, offering low-cost multidisciplinary publication with Crossref DOI and global indexing.

Subject Category: Research Area

Call for Paper: More Details

Approval, Licenses and Indexing: More Details