In-Vitro cytotoxicity effect of RUELLIA BRITONIANA flower on cervical Hela cancer cells.

Registration ID: IJNRD_300483

Published ID: IJNRDTH00195

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Chaithra

phytochemical constituents, biological, Ruellia, Acanthaceae

Cancer can be defined very broadly as disease in which there is uncontrolled multiplication and spreadwith in the body of abnormal forms of the body’s own cells. Strictly speaking ,one should use the term ‘neoplasm’ (mean ing a new growth) rather than the ‘cancer’.Neoplasms which have only the characteristic of localized growth are classified as ‘benign’.Neoplasms with the add itional characteristics of invasiveness and/or the capacity to metastasis are classified as ‘malignant’.The term cancer is usually applied only to this later types of growth.The word ‘tumour’ though in reality meaning ‘a local swelling’is also often use dinter changeably with cancer and will be soused now adays. According to the World Health Organisation estimates, cancer, which caused an unprecedented 9.6 million deaths in 2018 or one in six, and worldwide the second leading cause of mortality. The current treatment approaches of cancer include surgical operations, radiation induced therapy, chemotherapy, immune modulation therapy, targeted approaches, hormonal treatment, stem cell transplantation and precision medicine. Medicinal plants and their derivatives are widely accepted as effective alternative cancer therapies. A large number of clinical trials documented the effects of herbal medicinal products for cancer patients in conjunction with traditional therapeutics on recovery, immune modulation and quality of life. Ruellia is a genus of flowering plants commonly known as Ruellias or Wild Petunias which belongs to the family Acanthaceae. It contains about 250 genera and 2500 species. Most of these are shrubs, or twining vines; some are epiphytes. Only a few species are distributed in temperate regions. They are distributed in Indonesia and Malaysia, Africa, Brazil, Central America and Pakistan. Some of these are used as medicinal plants. Many species of the genus has antinociceptive, antioxidant, analgesic, antispasmolytic, antiulcer, antidiabetic and anti-inflammatory properties. The phytochemicals constituents: glycosides, alkaloids, flavonoids and triterpenoids have been found to be present in it. The genus has been traditionally claimed to be used for the treatment of flu, asthma, fever, bronchitis, high blood pressure, eczema, and diabetes. The objective of this research work was to understand the pharmacological and phytochemical aspects of this drug and to further find the gaps in research and endorse this genus as a step towards becoming a commercial drug. Hence, further work required is to isolate and characterize the active compounds responsible for these activities in this plant and bring this genus plants to commercial health market to serve the community with their potential benefits.

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Chaithra (September-2024). In-Vitro cytotoxicity effect of RUELLIA BRITONIANA flower on cervical Hela cancer cells.. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(9), 792-853. https://ijnrd.org/papers/IJNRDTH00195.pdf

Volume 9 Issue 9, September-2024

Pages : 792-853

Paper Reg. ID: IJNRD_300483

Published Paper Id: IJNRDTH00195

Research Area: Pharmacy All

Author Type: Indian Author

Country: bangalore, karnataka, India

Published Paper PDF: https://ijnrd.org/papers/IJNRDTH00195.pdf

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