Paper Title
FORMULATION, DEVELOPMENT AND EVALTUATION OF APREMILAST IMMEDIATE RELEASE TABLET FOR MANAGMENT OF PSORIATIC ARTHRITIS
Article Identifiers
Authors
PRIYANKA SUSHILKUMAR SARNIKAR , HINGNE L.D , BAGWAN LATIF RASHID
Keywords
Abstract
ABSTRACT: The aim of this research paper was to develop and evaluate an Apremilast immediate release tablet for the management of Psoriatic Arthritis by utilizing excipients and checking their compatibility with the API through preformulation studies. The tablets were formed using the direct compression method, and different trial batches were performed to check their activity.The preformulation studies showed that the selected excipients were compatible with the API, and the optimized formulation was found to have good flow and compressibility properties. The tablets were evaluated for their physical characteristics, including size, weight, and hardness. The in vitro dissolution studies were also conducted to assess the drug release profile of the developed tablets.The results of the study showed that the developed Apremilast immediate release tablets had excellent physical characteristics, with uniform size and weight. The in vitro dissolution studies indicated that the tablets had a quick release rate and met the required pharmacopoeial standards. The pharmacokinetic study revealed that the tablets exhibited rapid absorption, with a maximum plasma concentration achieved within 1 hour of administration.In conclusion, the developed Apremilast immediate release tablet utilizing excipients and preformulation studies has the potential to be an effective therapeutic option for the management of Psoriatic Arthritis. Further studies are required to investigate. Sometimes immediate onset of action is considered obligatory immediate release tablets are the final option. Recently immediate release tablets have started gaining popularity and acceptance as a drug delivery system, mainly because they are easy to administer and lead to better patient compliance. In the present work, we engage in discussion about formulation, development, and evaluation of immediate release tablets. An immediate release dosage form allows a manufacturer to extend market exclusivity. They are also a tool for expanding markets, extending product life cycles and generating opportunities. Pharmaceutical products designed for oral delivery and currently available on the prescription and over-the-counter markets are mostly the immediate release tablet.
Downloads
How To Cite (APA)
PRIYANKA SUSHILKUMAR SARNIKAR, HINGNE L.D , & BAGWAN LATIF RASHID (June-2023). FORMULATION, DEVELOPMENT AND EVALTUATION OF APREMILAST IMMEDIATE RELEASE TABLET FOR MANAGMENT OF PSORIATIC ARTHRITIS. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(6), 773-816. https://ijnrd.org/papers/IJNRDTH00050.pdf
Issue
Volume 8 Issue 6, June-2023
Pages : 773-816
Other Publication Details
Paper Reg. ID: IJNRD_197500
Published Paper Id: IJNRDTH00050
Downloads: 000121993
Research Area: Pharmacy
Country: Beed, Maharashtra , India
Published Paper PDF: https://ijnrd.org/papers/IJNRDTH00050.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRDTH00050
About Publisher
Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJNRD (IJ Publication) Janvi Wave | IJNRD.ORG | IJNRD.COM | IJPUB.ORG
Licence
This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
Publication Timeline
Article Preview: View Full Paper
Call For Paper
IJNRD is a Scholarly Open Access, Peer-reviewed, and Refereed Journal with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost Journal that follows UGC CARE 2025 Peer-Reviewed Journal Policy norms, Scopus journal standards, and Transparent Peer Review practices to ensure quality and credibility. IJNRD provides indexing in all major databases & metadata repositories, a citation generator, and Digital Object Identifier (DOI) for every published article with full open-access visibility.
The INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to advance applied, theoretical, and experimental research across diverse fields. Its goal is to promote global scientific information exchange among researchers, developers, engineers, academicians, and practitioners. IJNRD serves as a platform where educators and professionals can share research evidence, models of best practice, and innovative ideas, contributing to academic growth and industry relevance.
Indexing Coverage includes Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar (AI-Powered Research Tool), Microsoft Academic, Academia.edu, arXiv.org, ResearchGate, CiteSeerX, ResearcherID (Thomson Reuters), Mendeley, DocStoc, ISSUU, Scribd, and many more recognized academic repositories.
How to submit the paper?
By Our website
Click Here to Submit Paper Online
Important Dates for Current issue
Paper Submission Open For: October 2025
Current Issue: Volume 10 | Issue 10 | October 2025
Impact Factor: 8.76
Last Date for Paper Submission: Till 31-Oct-2025
Notification of Review Result: Within 1-2 Days after Submitting paper.
Publication of Paper: Within 01-02 Days after Submititng documents.
Frequency: Monthly (12 issue Annually).
Journal Type: IJNRD is an International Peer-reviewed, Refereed, and Open Access Journal with Transparent Peer Review as per the new UGC CARE 2025 guidelines, offering low-cost multidisciplinary publication with Crossref DOI and global indexing.
Subject Category: Research Area
Call for Paper: More Details
