FORMULATION AND EVALUVATION OF STAR ANISE FRUIT LOADED GRANULES FOR CARMANATIVE ACTIVITY

Registration ID: IJNRD_326610

Published ID: IJNRD2607117

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Asmana shaikh, Srushti Bhoir, Samidha Sonkambale, Dakshata Bhosale, Shraddha Kambale

Anethole, Antioxidant Activity, Bulk Density, Carminative Granules, Digestive Disorders.

The present study was aimed at the formulation and evaluation of Star Anise fruit (Illicium verum) loaded granules for carminative Activity. Herbal formulations are gaining increasing importance due to their better patient compliance, therapeutic effectiveness, low toxicity, and minimal side effects. Anethole, a major active constituent of Star Anise, possesses significant carminative, digestive, antispasmodic, antioxidant, and stomachic activities. The objective of the study was to develop a stable and effective herbal granule formulation for the treatment of flatulence, indigestion, gastric irritation, abdominal discomfort, and digestive disorders. The prepared granules were evaluated for various pharmacognosy, physicochemical, and phytochemical parameters. Morphological and microscopical evaluation confirmed the identity and purity of the crude drug. Physicochemical evaluation included determination of moisture content, total ash value, acid insoluble ash value, alcohol soluble extractive value, water soluble extractive value, pH, angle of repose, bulk density, tapped density, Carr’s index, Hausner ratio, and disintegration time. The results indicated that the granules possessed satisfactory flow properties and acceptable quality control parameters. The antioxidant activity of the prepared formulation was evaluated by DPPH free radical scavenging assay and showed significant antioxidant potential. Physiological studies demonstrated that the formulation effectively reduced flatulence, improved digestion, relieved abdominal discomfort, and showed mild antispasmodic activity without any significant adverse effects. The overall results of the study concluded that the formulated carminative granules containing Anethole exhibited good stability, satisfactory physicochemical characteristics, and promising therapeutic activity. The formulation can be considered as an effective and safe herbal dosage form for the management of digestive disorders and gastrointestinal discomfort.

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Asmana shaikh, Srushti Bhoir, Samidha Sonkambale, Dakshata Bhosale, & Shraddha Kambale (July-2026). FORMULATION AND EVALUVATION OF STAR ANISE FRUIT LOADED GRANULES FOR CARMANATIVE ACTIVITY. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 11(7), b182-b206. https://ijnrd.org/papers/IJNRD2607117.pdf

Volume 11 Issue 7, July-2026

Pages : b182-b206

Paper Reg. ID: IJNRD_326610

Published Paper Id: IJNRD2607117

Research Area: Pharmacy All

Author Type: Indian Author

Country: Thane, Maharastra, India

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