Paper Title
A Review Of Guggulu Formulations In Ayurveda: Pharmacological Properties And Clinical Applications.
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Registration ID: IJNRD_310686
Published ID: IJNRD2511272
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Keywords
Gugulu, Commiphora mukul, Ayurveda, anti-inflammatory, hypolipidemic, antioxidant
Abstract
Gugulu, obtained from the resin of Commiphora mukul, has been an integral component of Ayurvedic medicine for centuries, renowned for its diverse therapeutic applications. Traditionally, Gugulu has been employed in the management of metabolic disorders, obesity, hyperlipidemia, arthritis, and various inflammatory conditions. This review aims to comprehensively analyze both the traditional and modern scientific perspectives on Gugulu formulations, exploring their pharmacological properties, clinical relevance, and potential health benefits. Various Ayurvedic preparations, including Churna, Guggulu Taila, and Avaleha, exhibit notable therapeutic potential due to their anti-inflammatory, antioxidant, and hypolipidemic activities. Experimental studies have demonstrated that Gugulu and its formulations can modulate lipid metabolism, reduce oxidative stress, and inhibit inflammatory pathways, thereby supporting their use in cardiovascular and musculoskeletal disorders. Despite promising preclinical and clinical findings, there remains a lack of large-scale, standardized clinical trials that could fully validate these traditional claims. Moreover, variations in preparation methods, dosage forms, and treatment duration present challenges for consistent clinical application. This review also emphasizes the importance of integrating traditional Ayurvedic knowledge with contemporary scientific research to enhance evidence-based use of Gugulu in modern healthcare. By critically evaluating current literature, this article highlights both the therapeutic promise and the research gaps surrounding Gugulu formulations. Gugulu is generally well-tolerated, with mild gastrointestinal disturbances or rare allergic reactions reported; when used in polyherbal formulations, it may exhibit synergistic effects that enhance overall efficacy. Additionally, modern dosage forms such as capsules and tablets facilitate its incorporation into contemporary clinical practice. Overall, Gugulu represents a valuable herbal intervention with multifaceted benefits, bridging the gap between ancient Ayurvedic practices and contemporary pharmacological research, and offering potential avenues for novel therapeutic strategies in metabolic, inflammatory, and musculoskeletal disorders.
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How To Cite (APA)
Harsh Prabhakar Shimre, Mrs. Mayuri B. Mokal, Dr. D.K. Vir, Rushikesh Bhagwan Khule, & Abhishek Kashinath Shewale (November-2025). A Review Of Guggulu Formulations In Ayurveda: Pharmacological Properties And Clinical Applications.. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 10(11), c790-c801. https://ijnrd.org/papers/IJNRD2511272.pdf
Issue
Volume 10 Issue 11, November-2025
Pages : c790-c801
Other Publication Details
Paper Reg. ID: IJNRD_310686
Published Paper Id: IJNRD2511272
Research Area: Pharmacy All
Author Type: Indian Author
Country: Chhatrapati Sambhajinagar, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2511272.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2511272
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