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Paper Title

Next-Generation Nanoemulsion Gels: Bridging Nanotechnology and Herbal Medicine

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Registration ID: IJNRD_309127

Published ID: IJNRD2508260

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Keywords

Herbal Nanoemulgel, Topical Drug Delivery, Skin Penetration Enhancement, Bioavailability Enhancement, Controlled Drug Release.

Abstract

These gels work particularly well for applying medication on the skin and through it, as they help dissolve drugs better, allow them to penetrate the skin more effectively, and make it easier for patients to use them. Nanoemulsions are stable mixtures made up of oil, water, surfactants, and co-surfactants, with small droplets that usually measure between 20 and 200 nanometers. When these Nanoemulsions are mixed into a gel using ingredients like Carbopol 940, HPMC, or xanthan gum, the resulting Nanoemulgel becomes thicker, stays on the skin longer, and feels less greasy. These qualities lead to better treatment results. The tiny size of the droplets creates a wide surface area, allowing for improved contact with the skin and helping medicines to pass through the outer layer of the skin more easily. Both water-loving and fat-loving medications can be successfully mixed depending on how well they dissolve. The inclusion of surfactants and co-surfactants helps to break down the skin's fat layers, making it easier for substances to penetrate. Nanoemulgels have shown good effectiveness in delivering medicines for inflammation, fungal infections, bacterial infections, acne, and cancer treatment, among other uses. Physicochemical analysis, which involves checking things like pH, thickness, how easily a product spreads, how consistent the drug amount is, and how it releases in laboratory tests, is important for assessing the quality of a formulation. Franz diffusion cells are often utilized for studying how substances are released, and stability tests conducted according to ICH guidelines help confirm that the product remains effective over time. Because of their beneficial traits and versatility, Nanoemulsion gels are becoming a popular choice for both targeted and overall drug delivery, addressing the challenges faced by traditional topical products.

How To Cite (APA)

Prema Rathinam, Senthilkumar Chelladurai, Ananth Kathalingam, Ramya Singarayar,Chandrasekaran Gunasekaran, & Athiththiyan Sivakumar,Gowsalya Kasirajan (August-2025). Next-Generation Nanoemulsion Gels: Bridging Nanotechnology and Herbal Medicine. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 10(8), c464-c474. https://ijnrd.org/papers/IJNRD2508260.pdf

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Other Publication Details

Paper Reg. ID: IJNRD_309127

Published Paper Id: IJNRD2508260

Research Area: Pharmacy All

Author Type: Indian Author

Country: Nagapattinam, Tamil Nadu, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2508260.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2508260

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Publication Timeline

Paper Submission
20-08-2025
Peer Review
Through Scholar9.com Platform
Paper Acceptance
27-08-2025
Paper Publication
31-08-2025

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