Paper Title
FORMULATION AND EVALUATION OF FILMS FOR BUCCAL DRUG DELIVERY SYSTEM
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Registration ID: IJNRD_308780
Published ID: IJNRD2508062
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Keywords
Buccal films, Betaxolol HCl, Buccal drug delivery, solvent casting method, bioavailability enhancement, antihypertensive drug, mucoadhesive film
Abstract
The buccal drug delivery system (BDDS) is a novel and effective route for systemic drug administration through the buccal mucosa, offering advantages such as improved bioavailability, rapid onset of action, and avoidance of first-pass metabolism. Buccal dosage forms like films, tablets, and patches are thin, mucoadhesive, and easy to administer—making them especially suitable for paediatric, geriatric, and dysphagic patients.This system overcomes limitations of conventional oral delivery for drugs with poor gastrointestinal stability or low solubility. The formulation involves key components such as bioadhesive polymers, plasticizers, permeation enhancers, and flavoring agents. Common manufacturing methods include solvent casting and hot-melt extrusion. Evaluation parameters like mucoadhesive strength, film thickness, disintegration time, drug content, and in vitro drug release help assess product performance. Overall, BDDS represents a patient-friendly, non-invasive, and efficient alternative for systemic drug delivery with strong potential for future pharmaceutical applications.
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How To Cite (APA)
Sathe Sanchit & Dr. Gurav Yogesh Anant (August-2025). FORMULATION AND EVALUATION OF FILMS FOR BUCCAL DRUG DELIVERY SYSTEM . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 10(8), a662-a681. https://ijnrd.org/papers/IJNRD2508062.pdf
Issue
Volume 10 Issue 8, August-2025
Pages : a662-a681
Other Publication Details
Paper Reg. ID: IJNRD_308780
Published Paper Id: IJNRD2508062
Research Area: Pharmacy All
Author Type: Indian Author
Country: Akluj, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2508062.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2508062
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