Paper Title
DEVELOPMENT AND IN-VITRO CHRATERIZATION OF CUBOSOMAL GEL FOR TOPICAL DELIVERY OF CELECOXIB FOR TREATMENT OF RHEUMATOID ARTHRITIS.
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DEVELOPMENT AND IN-VITRO CHRATERIZATION OF CUBOSOMAL GEL FOR TOPICAL DELIVERY OF CELECOXIB FOR TREATMENT OF RHEUMATOID ARTHRITIS.
Abstract
Rheumatoid Arthritis (RA) is auto immune disorder causes inflammation in joints resulting pain & deformity in wrist, fingers and ankles. This disease arises in women more than men at any age. The manifestation of disease includes redness, inflammation.[1] Early diagnosis is important for improvement of symptoms but quite difficult to detect at early age as it depends upon gathering clinical information & history of patient. There is no permanent therapy to treat rheumatoid arthritis. For complete suppression of disease symptoms, rheumatologist need to observe activity constantly and correctly to adjust treatment schedule. From last 20 years, Disease modifying anti-rheumatoid drugs (DMARDs) has gained much attention because of their effectiveness and can efficiently reduce the activity of disease and considerably decrease the joint deformity. In current therapies DMARDS are rarely implemented for the treatment of disease. Several new biological DMARDS such as anti-CD20 antibody, TNF inhibitors etc. With increase in the number of drugs and treatment options available, the long term disease remission is not achieved in many cases and thus new therapeutic options are still needed.[2,3] The reason of occurring the rheumatoid arthritis is not clear till date, it is supposed that the disease occurs due to various genetic and environment factors. The disease causes the inflammation and thickening of the joint which occurs due to the immature system of the body directly attacking the joints. The disease may also result in low blood cell count, inflammation nearby the lungs and heart.
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Masood Iftikhar, Dr. Praveen Kumar, & Kritika Badola (August-2025). DEVELOPMENT AND IN-VITRO CHRATERIZATION OF CUBOSOMAL GEL FOR TOPICAL DELIVERY OF CELECOXIB FOR TREATMENT OF RHEUMATOID ARTHRITIS.. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 10(8), a448-a455. https://ijnrd.org/papers/IJNRD2508045.pdf
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Volume 10 Issue 8, August-2025
Pages : a448-a455
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Paper Reg. ID: IJNRD_308751
Published Paper Id: IJNRD2508045
Downloads: 000121995
Research Area: Science and Technology
Author Type: Indian Author
Country: -, -, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2508045.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2508045
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