Paper Title
In Silico Assessment of Artemisia vulgaris Anti-Angiogenic Potential through Molecular Docking Against VEGFR, VEGF, PDGF, and FGF2
Article Identifiers
Authors
Ms. Snehal Jadhav , Dr. Pradnya N. Jagtap , Mr. Saurabh Kudale , Ms. Nikita Jagtap
Keywords
Artemisia vulgaris, Angiogenesis, Molecular Docking, Anti-angiogenic Agents
Abstract
The potential anti-angiogenic activity of Artemisia vulgaris, a medicinal plant with various pharmacological characteristics, was assessed through in silico molecular docking studies. Normal development and diseases such as cancer, diabetic retinopathy, and rheumatoid arthritis rely on the physiological process of angiogenesis, which creates new blood vessels from existing vasculature. Angiogenesis, the physiological process by which new blood vessels are formed from pre-existing vasculature, is crucial for normal development and conditions like cancer, diabetic retinopathy, and rheumatoid arthritis. This process is tightly regulated by several growth factors and their receptors. In this study, key phytoconstituents of Artemisia vulgaris were docked against these angiogenesis-related proteins to assess their potential as inhibitors. The binding affinities and interaction profiles of several compounds from Artemisia vulgaris revealed strong binding to the target proteins, which may suggest that they modulate angiogenic signaling pathways. The therapeutic potential of Artemisia vulgaris as a natural source of anti-angiogenic agents is supported by these findings.
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How To Cite (APA)
Ms. Snehal Jadhav, Dr. Pradnya N. Jagtap, Mr. Saurabh Kudale, & Ms. Nikita Jagtap (May-2025). In Silico Assessment of Artemisia vulgaris Anti-Angiogenic Potential through Molecular Docking Against VEGFR, VEGF, PDGF, and FGF2. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 10(5), a544-a556. https://ijnrd.org/papers/IJNRD2505047.pdf
Issue
Volume 10 Issue 5, May-2025
Pages : a544-a556
Other Publication Details
Paper Reg. ID: IJNRD_306408
Published Paper Id: IJNRD2505047
Downloads: 000121985
Research Area: Pharmacy All
Country: Pune, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2505047.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2505047
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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Paper Submission Open For: October 2025
Current Issue: Volume 10 | Issue 10 | October 2025
Impact Factor: 8.76
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