ARUGABON: A FORMULATED ORGANIC OPEN WOUND-HEALING OINTMENT USING SAMBONG (Blumea balsamifera) LEAF EXTRACTS WITH GUAVA (Psidium guajava) SCENT

Registration ID: IJNRD_304302

Published ID: IJNRD2503333

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MIKA-ELLA HARINDER C. WAHANI, JAY BRIAN T. MONINO, ORLY Q. GANTALA, SHARIFA C. MAHAMOD, BAINARA B. ACOT

Open wound-healing ointment, sambong, guava, antibacterial properties, pH Level, Irritation, Wound-Healing Properties, Tensile Strength

This study evaluated the efficacy of a formulated organic open wound-healing ointment using Sambong (Blumea balsamifera) leaf extract with Guava (Psidium guajava) scent. The organic formulation, comprising plant-based extracts and oils, demonstrated notable therapeutic effects. At a 50% concentration, Sambong extract significantly reduced wound size by 94.48%, slightly lower than Betadine ointment’s 97.76% reduction. However, Sambong-treated wounds exhibited higher tensile strength (73.39 g/mm²) compared to Betadine (13.51 g/mm²) and distilled water (10.33 g/mm²), suggesting stronger, more resilient healed tissue. Sambong also showed partial antibacterial activity against Staphylococcus aureus, with a zone of inhibition between 9-10 mm, contributing to wound healing by potentially reducing bacterial colonization. The ointment’s pH (5.33) aligns with the natural skin pH, promoting an optimal environment for healing without disrupting the skin barrier. Additionally, patch tests indicated no adverse reactions, highlighting its safety for skin use. Statistical analysis confirmed significant differences in wound reduction, antibacterial efficacy, and body weight changes among groups, with the Sambong group showing a slight weight reduction. While Betadine was slightly more effective in reducing wound area, the higher tensile strength of Sambong-treated wounds suggests better wound integrity, beneficial for complex or deeper wounds. In sum, this Sambong-based ointment shows promise as a natural alternative or complement to conventional wound treatments, with further research recommended to enhance its antibacterial properties and examine histopathological healing characteristics.

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MIKA-ELLA HARINDER C. WAHANI, JAY BRIAN T. MONINO, ORLY Q. GANTALA, SHARIFA C. MAHAMOD, & BAINARA B. ACOT (March-2025). ARUGABON: A FORMULATED ORGANIC OPEN WOUND-HEALING OINTMENT USING SAMBONG (Blumea balsamifera) LEAF EXTRACTS WITH GUAVA (Psidium guajava) SCENT. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 10(3), d291-d306. https://ijnrd.org/papers/IJNRD2503333.pdf

Volume 10 Issue 3, March-2025

Pages : d291-d306

Paper Reg. ID: IJNRD_304302

Published Paper Id: IJNRD2503333

Research Area: Life Sciences All

Author Type: Foreign Author

Country: Alabel, Sarangani, Philippines

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