FAST DISSOLVING SUBLINGUAL FILMS AS A PROMISING DRUG DELIVERY ROUTE

Registration ID: IJNRD_302814

Published ID: IJNRD2412208

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Ms. Yogita S. Khaire, Dr. Rajashree S. Chavan, Mr. Nilesh R. Bhosale, Mr. santosh A. Katkure, Ms. Isha P. Dhole

Fast dissolving films, Sublingual route, Bypass first pass metabolism, Rapid onset of action, solvent casting and disintegration, oral strips, polymer.

As an alternative to traditional dosage forms, fast dissolving drug delivery systems were initially created in the late 1970s. These systems are made up of solid dose forms that dissolve and break down rapidly in the mouth without the need for water. Oral thin films (OTFs) and oral disintegrating tablets (ODTs) are examples of fast-dissolving drug delivery systems. Drugs can enter the body by a variety of ways, including parenteral, buccal, sublingual, oral, transdermal, and rectal. Among these, the sublingual route of administration is a promising strategy for getting medications into the systemic circulation. Sublingual films offer a special chance to act as drug carriers and may release the medication rapidly into the sublingual area for immediate absorption and impact. Because the medicine has a higher bioavailability and passes through the hepatic first-pass metabolic process, the sublingual route of drug administration is particularly useful for providing speedier relief. a number of variables, including the salivary glands' production, other physiological variables, and the drug's physiochemical characteristics, such as its hydrophobicity, ability to attach to the oral mucosa, epithelial thickness, etc. The development of an effective sublingual film medication delivery device requires consideration of these factors. Sublingual films can be evaluated using a variety of criteria, including tensile strength, weight fluctuation, and thickness.

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Ms. Yogita S. Khaire, Dr. Rajashree S. Chavan, Mr. Nilesh R. Bhosale, Mr. santosh A. Katkure, & Ms. Isha P. Dhole (December-2024). FAST DISSOLVING SUBLINGUAL FILMS AS A PROMISING DRUG DELIVERY ROUTE. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(12), c45-c52. https://ijnrd.org/papers/IJNRD2412208.pdf

Volume 9 Issue 12, December-2024

Pages : c45-c52

Paper Reg. ID: IJNRD_302814

Published Paper Id: IJNRD2412208

Research Area: Pharmacy All

Author Type: Indian Author

Country: Jejuri, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2412208.pdf

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