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Paper Title

A review article on anaesthesia and analgesia in labaratory animals

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Registration ID: IJNRD_301947

Published ID: IJNRD2411240

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Keywords

Keywords: Anaesthesia, analgesia, laboratory animals, pain management, humane treatment, multimodal analgesia, ethical research, animal welfare.

Abstract

Anaesthesia and analgesia are major components of the ethical practice in the use of lab animals in biomedical research. From these sources it is seen that these interventions are necessary under circumstances where it becomes essential to reduce suffering, discomfort and anxiety to the subjects being experimented on. Proper anaesthetic regimens promote humane handling of animals that are subjected to surgery or other procedures requiring invasion of the body. There are many different anaesthetic agents with inhalational, intravenous and other types of anaesthetics with the choice dependent on species, size, age, overall health and specific needs of the procedure.Analgesia is equally as important as anaesthetics being the relief of pain before, during and after surgery interference. Pain relievers include NSAIDs, opioids and local anesthetics, and they help the animals to free from severe pain that threaten its welfare. New modalities have also added to multimodal analgesia, a technique that aims at using several types of analgesics to have better pain relief than a single one without side effects. Considering depth of anaesthesia and quality of analgesia is especially imperative in terms of animal welfare and possibly for contribution to experiment results. Both physiological and behaviour monitoring methods are used to identify the correct plane of anaesthesia and analgesia. However, legal requirements and ethical concerns define protocols related to the use of anesthesia and analgesia in laboratories. Specifically, animal reviewers belong to an Institutional Animal Care and Use Committees (IACUCs) of an institution and their function is to provide a check that a proposed or ongoing research use animals in a humane way, minimizing the levels of pain and suffering as much as is feasible.

How To Cite (APA)

S. Shaheena Begum & N. Madhuri (November-2024). A review article on anaesthesia and analgesia in labaratory animals. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(11), c352-c367. https://ijnrd.org/papers/IJNRD2411240.pdf

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Other Publication Details

Paper Reg. ID: IJNRD_301947

Published Paper Id: IJNRD2411240

Research Area: Pharmacy All

Author Type: Indian Author

Country: Kurnool, Andhra Pradesh, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2411240.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2411240

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