Breast cancer

Registration ID: IJNRD_300224

Published ID: IJNRD2409117

DOI: Click Here to Get

Kranti Nandalal sonawane , Vrushali Dnyaneshwar bhabd , Mansi kashinath sanap , Suvarna Anna pavar , Harshad santosha shinde

Keywords: cancer, breast cancer, women, gene

Abstract: Breast cancer is the most frequently diagnosed cancer in women and ranks second among causes for cancer related death in women. The ability to identify and diagnose breast cancer has improved markedly. Treatment decisions which were based in the past predominantly on the anatomic extent of the disease are shifting to the underlying biological mechanisms. Gene array technology has led to the recognition that breast cancer is a heterogeneous disease composed of different biological subtypes, and genetic profiling enables response to chemotherapy to be predicted. Breast conservation became an established standard of care and the oncoplastic approach enables wide excisions without compromising the natural shape of the breast. Sentinel lymph node biopsy has replaced axillary dissection as the standard procedure to stage the axilla and spared many patients the excess morbidity of axillary dissection. Targeted therapy to the oestrogen receptor plays a major role in systemic therapy; pathways responsible for endocrine resistance have been targeted as well. Biological therapy has been developed to target HER2 receptor and combination of antibody drug conjugates linked cytotoxic therapy to HER2 antibodies. Meaningful improvements in survival resulted from the new effective systemic agents and patients with metastasis are likely to have a longer survival.

Published Paper   E-Certificate

Kranti Nandalal sonawane, Vrushali Dnyaneshwar bhabd, Mansi kashinath sanap, Suvarna Anna pavar, & Harshad santosha shinde (September-2024). Breast cancer . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(9), b146-b161. https://ijnrd.org/papers/IJNRD2409117.pdf

Volume 9 Issue 9, September-2024

Pages : b146-b161

Paper Reg. ID: IJNRD_300224

Published Paper Id: IJNRD2409117

Downloads: 000121983

Research Area: Pharmacy All

Country: Kalavan/nashik , Maharashtra , India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2409117.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2409117

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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