Paper Title
To study the cause, outcome and complications amongst newborns requiring exchange transfusion
Article Identifiers
Authors
DR.SHRUTI RAJAMANI , DR.RUPALI JAIN , DR.VIKAS GUPTA
Keywords
Exchange transfusion, hyperbilirubinemia
Abstract
INTRODUCTION- Treatment modalities for significant hyperbilirubinemia are phototherapy and exchange transfusion. Exchange transfusion in newborns is recommended as emergency management of hyperbilirubinemia and as an effective method to achieve safe bilirubin level in infants at high risk of kernicterus. AIMS AND OBJECTIVES- To study the cause, outcome and complications amongst newborns requiring exchange transfusion. MATERIALS AND METHODS- Retrospective observational study. Data was obtained from neonatal intensive care unit of a tertiary care hospital, in Navi Mumbai, from April 2022 to January 2024. A total of 10 such cases were studied. RESULTS- Amongst the babies who required exchange transfusion, 90% of the cases were outborn cases. While 90% babies were of term gestation, late preterm gestation was noted in only 1 case. Exchange transfusion was performed two times for 20% cases. Analysis of the cause revealed that 50% cases had Rh incompatibility, with a Positive Coomb’s test noted in 20% cases. ABO incompatibility was noted in 30% cases, Hirschsprung’s disease was diagnosed in 1 case, whereas 1 case had significant weight loss. Umbilical Vein Catheterization was done in 90% cases. The procedure was tolerated well by all cases. Commonly observed complications were hypokalemia, hypocalcemia, hyperglycemia, thrombocytopenia and sepsis. Bilirubin encephalopathy was noted in 20% cases, who had presented with a high Bilirubin Induced Neurological Dysfunction (BIND) score. No mortalities were recorded. CONCLUSION- Most common causes for hyperbilirubinemia needing exchange transfusion are Rh incompatibility and ABO incompatibility. In conclusion, exchange transfusion is effective in reducing serum bilirubin value and in preventing kernicterus.
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DR.SHRUTI RAJAMANI, DR.RUPALI JAIN, & DR.VIKAS GUPTA (September-2024). To study the cause, outcome and complications amongst newborns requiring exchange transfusion. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(9), a506-a509. https://ijnrd.org/papers/IJNRD2409055.pdf
Issue
Volume 9 Issue 9, September-2024
Pages : a506-a509
Other Publication Details
Paper Reg. ID: IJNRD_300025
Published Paper Id: IJNRD2409055
Downloads: 000121985
Research Area: Humanities All
Country: MUMBAI, MAHARASHTRA, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2409055.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2409055
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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