Prevalence and Determinants of Herpes Simplex Virus type 2: A Rural-Urban Comparison among HIV-Infected and Uninfected Pregnant Women in Cross River State, Nigeria

Prevalence and Determinants of Herpes Simplex Virus type 2: A Rural-Urban Comparison among HIV-Infected and Uninfected Pregnant Women in Cross River State, Nigeria

Registration ID: IJNRD_226465

Published ID: IJNRD2408205

DOI: Click Here to Get

Sylvester E Abeshi , Chiegina O Godwin , Ezukwa O Ezukwa , Edet E Ekpo

Herpes simplex virus, Human immunodeficiency virus, Seroprevalence, Enzyme-linked immunosorbent test.

ABSTRACT: Preventing neonatal herpes is a crucial step in combating herpes simplex virus infection. Knowing the HSV status of the mother is advantageous. Furthermore, HSV infection serves as a biological cofactor for HIV infection, a disease that has reached pandemic levels. Conducting screenings on pregnant women for HSV infection would enable the identification of women who are at risk and facilitate measures to prevent neonatal infection. GOAL: To assess and contrast the occurrence rate of HSV type 2 in pregnant women who are infected with HIV and those who are not infected with HIV. PROCEDURE: Serum samples from a total of 300 pregnant women, with 150 being HIV infected and 150 being HIV uninfected, were examined for the presence of HSV-2 IgG antibodies. Female participants who were less than 36 weeks pregnant got optional counselling, followed by testing for their HIV and HSV-2 status using a commercially available kit called CALBIOTECH HSV-2 IgG ELISA. The study aimed to establish the seroprevalence of HSV type 2, as well as the prevalence of HSV type 2 and HIV co-infection. A seroprevalence comparison was conducted between customers infected with HIV and clients not infected with HIV to determine the prevalence of HSV type 2. A comparison was also conducted between rural and urban areas regarding the incidence of HSV type 2. The data collected were analysed using the Statistical Package for the Social Sciences (SPSS). The researchers employed multivariate logistic regression to determine the independent factors that predict HSV type 2 infections. The prevalence of HSV-2 among pregnant women infected with HIV was 83.3%, whereas it was 80.7% among pregnant women not infected with HIV. Among rural inhabitants, the prevalence was 74.4%, while among urban dwellers, it was 87.4%. The factors that were shown to be linked with HSV-2 seropositivity were the level of knowledge about HSV-2 (X2=5.426; p=0.020), the location of the responder (X2=13.102; p=0.001), and the age of the spouse (FET;9.933, p=0.047). The age of the spouse was found to be a significant predictor of HVS type 2 seropositivity, as determined by a multivariate binary logistic regression analysis. CONCLUSION: The incidence of HSV-2 is considerably elevated among pregnant women in Cross River state, Nigeria. It is necessary to formulate methods with the objective of decreasing HSV-2 infection rates among pregnant women.

Published Paper   E-Certificate

"Prevalence and Determinants of Herpes Simplex Virus type 2: A Rural-Urban Comparison among HIV-Infected and Uninfected Pregnant Women in Cross River State, Nigeria", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 8, page no.c36-c47, August-2024, Available :https://ijnrd.org/papers/IJNRD2408205.pdf

Volume 9 Issue 8, August-2024

Pages : c36-c47

Paper Reg. ID: IJNRD_226465

Published Paper Id: IJNRD2408205

Downloads: 000121217

Research Area: Medical Science

Country: Calabar, Cross River State, Nigeria

Published Paper PDF: https://ijnrd.org/papers/IJNRD2408205.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2408205

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

Call For Paper - Volume 10 | Issue 8 | August 2025

IJNRD is Scholarly open access journals, Peer-reviewed, and Refereed Journals, High Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool), Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) with Open-Access Publications.

INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world. IJNRD will provide an opportunity for practitioners and educators of engineering field to exchange research evidence, models of best practice and innovative ideas.

Indexing In Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar | AI-Powered Research Tool, Microsoft Academic, Academia.edu, arXiv.org, Research Gate, CiteSeerX, ResearcherID Thomson Reuters, Mendeley : reference manager, DocStoc, ISSUU, Scribd, and many more

How to submit the paper?

Important Dates for Current issue

Paper Submission Open For: August 2025

Current Issue: Volume 10 | Issue 8

Last Date for Paper Submission: Till 31-Aug-2025

Notification of Review Result: Within 1-2 Days after Submitting paper.

Publication of Paper: Within 01-02 Days after Submititng documents.

Frequency: Monthly (12 issue Annually).

Journal Type: International Peer-reviewed, Refereed, and Open Access Journal.

Subject Category: Research Area