Paper Title
Biological Evaluation of Alcoholic Extract of Origanum majorana On Diabetic Wound Healing In Rats.
Article Identifiers
Authors
Arushi jain , Dr. Ayush Modi , Dr. Harshita jain
Keywords
Keywords: Wound healing, Origanum mjorana, , Diabetes mellitus.
Abstract
Objectives:- The aim of this study was to investigate the effects of Origanum mjorana(OM) , a known flavonoid, and its Pharmacological action .when topically applied to the diabetic wound. Origanum mjorana (OM) have been extensively documented for its pharmacological values, but its application in wound healing in particular in a diabetic wound healing model is less documented. Methods: In our study, alloxan-induced diabetic rats were used as a chronic delayed wound model and topical administration of OM were used to assess the role and function of OM in wound healing through wound contraction . Results: we found out that OM accelerated wound healing in post-wounding day 3 (inflammatory phase), whereas aggressively decelerating wound healing in post-wounding day 7 (proliferation phase). and is further decelerated at post-wounding day 15. Although insignificant, average Size of wound contraction. Conclusions: Our study shows that OM accelerates wound healing during the inflammatory phase; however, decelerate rapidly during the proliferation phase. We speculate the acceleration of wound healing during the inflammatory phase was due to its well-documented antioxidant, anti-inflammatory, and antimicrobial properties while its deceleration of wound healing during the proliferation phase was due to its well-documented antiangiogenic effect.
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How To Cite (APA)
Arushi jain, Dr. Ayush Modi, & Dr. Harshita jain (July-2024). Biological Evaluation of Alcoholic Extract of Origanum majorana On Diabetic Wound Healing In Rats.. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(7), c405-c420. https://ijnrd.org/papers/IJNRD2407244.pdf
Issue
Volume 9 Issue 7, July-2024
Pages : c405-c420
Other Publication Details
Paper Reg. ID: IJNRD_225263
Published Paper Id: IJNRD2407244
Downloads: 000121979
Research Area: Pharmacy
Country: lalitpur, uttar pradesh, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2407244.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2407244
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