Neurobehavioral and Neurochemical of Effect of Azadirachta Indica on Stress Induced Anxiety in Mice

Registration ID: IJNRD_225085

Published ID: IJNRD2407182

: Click Here to Get

Ms. Jyoti Rajput, Mr. Akash Sharma

Azadirachta indica A. Juss, Synthetic drugs, Mice, Extract, Effect, Dose, Toxicity.

Anxiety disorder is common mental disorders that share extreme or pathological anxiety as the primary disturbance in mood or emotional tone. Biochemical alteration are observed in anatomical centers, which are responsible for processing of emotions and are connected to ―stress‖ axis , which is strongly activated in response to threat or fear. The imbalances in the neurotransmitters like GABA, Serotonin, nor adrenaline, Dopamine etc mainly causes anxiety disorders. Synthetic drugs available for treatment of anxiety have various adverse effects including drowsiness, ataxia with benzodiazepines and insomnia, libido with selective serotonin reuptake inhibitors. Azadirachta indica A. Juss, common name Neem, Neem tree, Indian-lilac (Canada), Margosa, Nimtree and mMrgosier, family Maliacea, responsible for some of the already mentioned neem benefits, they are known to possess immunomodulatory, antiinflammatory, antihyperglycaemic, antiulcer, antimalarial, antifungal, antibacterial, antiviral, antioxidant, antimutagenic and anti-carcinogenic properties being one of the most active parts of the plant. Behavioral parameters are the primary evidence to confirm anxiety as well as anti-anxiety effect of treatments. All the parameters are based on pathophysilogy of anxiety because anxiety or fear is evaluated through stress or immobilization of animal like mice and rats. On the bases of behavioral parameters as well as biochemical estimation, study concludes that Azadirachta indica shows significant effect in plasma nitrates and other chemical messenger in anxiety at dose of 200mg/kg

Published Paper   E-Certificate

Ms. Jyoti Rajput & Mr. Akash Sharma (July-2024). Neurobehavioral and Neurochemical of Effect of Azadirachta Indica on Stress Induced Anxiety in Mice. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(7), b786-b792. https://ijnrd.org/papers/IJNRD2407182.pdf

Volume 9 Issue 7, July-2024

Pages : b786-b792

Paper Reg. ID: IJNRD_225085

Published Paper Id: IJNRD2407182

Downloads: 000122008

Research Area: Pharmacy

Author Type: Indian Author

Country: Sagar, Madhya Pradesh, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2407182.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2407182

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

UGC CARE JOURNAL PUBLICATION | ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave | IJNRD.ORG | IJNRD.COM | IJPUB.ORG

© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License. and The Open Definition.

You are free to share, adapt, and redistribute the material, provided proper credit is given to the original author. 🛡️ Disclaimer: The content, data, and findings in this article are based on the authors’ research and have been peer-reviewed for academic purposes only. Readers are advised to verify all information before practical or commercial use. The journal and its editorial board are not liable for any errors, losses, or consequences arising from its use.

Call For Paper - Volume 10 | Issue 12 | December 2025

IJNRD is a Scholarly Open Access, Peer-Reviewed, Refereed, and UGC CARE Journal Publication with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost, and Transparent Peer Review Journal Publication that adheres to the UGC CARE 2025 Peer-Reviewed Journal Policy and aligns with Scopus Journal Publication standards to ensure the highest level of research quality and credibility.

IJNRD offers comprehensive Journal Publication Services including indexing in all major databases and metadata repositories, Digital Object Identifier (Crossref DOI) assignment for each published article with additional fees, citation generation tools, and full Open Access visibility to enhance global research reach and citation impact.

The INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to advance applied, theoretical, and experimental research across diverse academic and professional fields. The journal promotes global knowledge exchange among researchers, developers, academicians, engineers, and practitioners, serving as a trusted platform for innovative, peer-reviewed journal publication and scientific collaboration.

Indexing Coverage: Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar (AI-Powered Research Tool), Microsoft Academic, Academia.edu, arXiv.org, ResearchGate, CiteSeerX, ResearcherID (Thomson Reuters), Mendeley, DocStoc, ISSUU, Scribd, and many other recognized academic repositories.

How to submit the paper?

By Our website

Click Here to Submit Paper Online

By Mail

Send your paper to editor@ijnrd.org

You can now publish your research in IJNRD. IJNRD is a Transparent Peer-Reviewed Open Access Journal Publication (Refereed Journal), aligning with New UGC and UGC CARE recommendations.

For more details, refer to the official notice: UGC Public Notice

Submit Paper Online

Important Dates for Current issue

Paper Submission Open For: December 2025

Current Issue: Volume 10 | Issue 12 | December 2025

Impact Factor: 8.76

Last Date for Paper Submission: Till 31-Dec-2025

Notification of Review Result: Within 1-2 Days after Submitting paper.

Publication of Paper: Within 01-02 Days after Submititng documents.

Frequency: Monthly (12 issue Annually).

Journal Type: IJNRD is an International Peer-reviewed, Refereed, and Open Access Journal with Transparent Peer Review as per the new UGC CARE 2025 guidelines, offering low-cost multidisciplinary publication with Crossref DOI and global indexing.

Subject Category: Research Area

Call for Paper: More Details

Approval, Licenses and Indexing: More Details