ASSESSMENT OF THE WOUND HEALING EFFICACY OF PODOPHYLLOTOXIN IN STREPTOZOTOCIN – INDUCED DIABETIC RATS

Registration ID: IJNRD_224905

Published ID: IJNRD2407141

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Said Abdullahi Said , Ms. Arti Kumari, Ms Nidhi Sharma

This Research gives a detailed overview of preparations of oinments, Thin Layer chromatography Analysis, phytochemical Screaning inducing of animals, weight of animals food consuming histopathology.

The study and evaluated the wound healing activity of Podophyllotoxin in streptozotocin-induced diabetic in rats. Podophyllotoxin, a natural compound with known cytotoxic properties against wound healing enhanced, was examined for its potential to aid in wound healing, especially under diabetic conditions where wound healing is impaired. The research likely assessed parameters such as wound closure rate, histopathological biochemical changes, inflammatory response, and oxidative stress markers in diabetic animal models treated with Podophyllotoxin. The findings could provide insights into the therapeutic potential of Podophyllotoxin in managing diabetic wound healing complications. Diabetes is a prevalent metabolic disorder that results in a delayed wound-healing process. Growing evidence proved that impaired glucose homeostasis is an independent risk factor for the occurrence of various types of diabetes including type 1 diabetes, type 2 diabetes, type 3 diabetes, and type 4 diabetes. Wound healing becomes the most severe complication of diabetic patients. Diabetes mellitus has a strong relationship with the healing process, thus there is a need to look for drugs that can be beneficial in maintaining glycemic levels as well as enhancing the process of healing. Therefore, more research is focusing on evaluating the role of antihyperglycemic agents in the wound-healing process. Metformin, sulfonylureas, and Insulin are the drugs that are used to enhance the wound-healing process in diabetics. This Research gives a detailed overview of preparations of oinments, Thin Layer chromatography Analysis, phytochemical Screaning inducing of animals, weight of animals food consuming histopathology.

Published Paper   E-Certificate

Said Abdullahi Said , Ms. Arti Kumari, & Ms Nidhi Sharma (July-2024). ASSESSMENT OF THE WOUND HEALING EFFICACY OF PODOPHYLLOTOXIN IN STREPTOZOTOCIN – INDUCED DIABETIC RATS. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(7), b377-b392. https://ijnrd.org/papers/IJNRD2407141.pdf

Volume 9 Issue 7, July-2024

Pages : b377-b392

Paper Reg. ID: IJNRD_224905

Published Paper Id: IJNRD2407141

Downloads: 000122017

Research Area: Pharmacy

Author Type: Foreign Author

Country: Gurguan, Haryana, Nigeria

Published Paper PDF: https://ijnrd.org/papers/IJNRD2407141.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2407141

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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