Paper Title
Comparative Study Of Evaluation Of Generic And Branded Metformin HCL (500mg) Tablets
Article Identifiers
Registration ID: IJNRD_224979
Published ID: IJNRD2407137
DOI: http://doi.one/10.1729/Journal.40489
Authors
Mansi Kishor Mulik , Vaibhav Shashikant Patil , Rohan R. Vakhariya
Keywords
Generic drugs, patent, metformin, evaluation, quality.
Abstract
The use of generic or branded drugs is gaining attention globally, with governments promoting the use of generics over branded ones. Metformin hydrochloride, a first-line anti-diabetic drug, is used for treating type II diabetes, particularly in obese patients. Various brands of metformin are available, making it challenging to select an effective and economical option. This research aimed to compare and evaluate the performance of different marketed brands of generic and branded metformin tablets. Two 500 mg tablets were selected and evaluated for their physical and chemical parameters. The physicochemical equivalence of all brands was determined using official standards, including thickness, hardness, weight variation, friability, disintegration time, standard calibration curve, dissolution study, and drug content. The results showed that all brands were within acceptable range, following IP specifications. It is recommended that further research be conducted in different formulations to ensure product quality.
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How To Cite (APA)
Mansi Kishor Mulik, Vaibhav Shashikant Patil, & Rohan R. Vakhariya (July-2024). Comparative Study Of Evaluation Of Generic And Branded Metformin HCL (500mg) Tablets. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(7), b338-b351. http://doi.one/10.1729/Journal.40489
Issue
Volume 9 Issue 7, July-2024
Pages : b338-b351
Other Publication Details
Paper Reg. ID: IJNRD_224979
Published Paper Id: IJNRD2407137
Downloads: 000121999
Research Area: Pharmacy
Country: Sangali, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2407137.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2407137
Crossref DOI: http://doi.one/10.1729/Journal.40489
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition


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