Paper Title
Titanium Platelet Rich Fibrin(T-PRF): A Superior Choice Over Conventional Platelet Concentrates
Article Identifiers
Authors
Dr Lisa Chacko , Dr Shivani Anand Karmalkar , Dr Purushottam Rakhewar , Dr Sakshi Vidhale , Dr Priyanka Kurdukar
Keywords
T-PRF, Titanium, Platelet concentrates, L-PRF
Abstract
INTRODUCTION- Titanium-Prepared Platelet-Rich Fibrin (T-PRF) represents an advanced modality in the field of regenerative medicine, leveraging the synergistic effects of titanium and autologous platelet concentrates to enhance tissue healing and regeneration. AIM-This review aims to provide a detailed examination of T-PRF, focusing on its preparation, properties, and clinical applications. SIGNIFICANCE OF T-PRF- The clinical use of glass coated plastic tubes with silica activators for the preparation of platelet concentrates may cause potential health concerns because of possible cytotoxicity of silica. Hence instead of glass coated tubes, the use of medical-grade IV titanium tubes for PRF preparation is relevant and safe. The development of third generation concentrate i.e. T-PRF (Tunali et al 2014) is based on the hypothesis that titanium tubes might be more effective in activating platelets than the glass tubes used in Choukroun's platelet-rich fibrin (PRF) method. Titanium has one of the highest strength-to-weight ratios and corrosion resistance among metals offering improved hemocompatibility, platelet activation similar to silica, and the advantage of reusability after proper sterilization, while being durable. The incorporation of titanium is hypothesized to enhance the stability and release of growth factors, thereby promoting superior regenerative outcomes compared to traditional PRF. Furthermore, it evaluates the clinical evidence supporting its use in various dental applications, such as periodontal therapy, bone grafting and soft tissue repair. Emerging studies indicate that T-PRF offers significant advantages in terms of biocompatibility, growth factor release, and mechanical properties. CONCLUSION- T-PRF emerges as a promising tool in regenerative medicine, with the potential to enhance clinical outcomes through its unique preparation and biological properties.
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How To Cite (APA)
Dr Lisa Chacko, Dr Shivani Anand Karmalkar, Dr Purushottam Rakhewar, Dr Sakshi Vidhale , & Dr Priyanka Kurdukar (July-2024). Titanium Platelet Rich Fibrin(T-PRF): A Superior Choice Over Conventional Platelet Concentrates. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(7), b253-b262. https://ijnrd.org/papers/IJNRD2407128.pdf
Issue
Volume 9 Issue 7, July-2024
Pages : b253-b262
Other Publication Details
Paper Reg. ID: IJNRD_224949
Published Paper Id: IJNRD2407128
Downloads: 000122003
Research Area: Medical Science
Country: AhmedNagar, Maharasthtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2407128.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2407128
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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