Paper Title
Clinical and Epidemiological Perspectives on Salmonella Typhimurium: A Comprehensive Review of Pathogenesis, Antibiotic Resistance, and Public Health Implications
Article Identifiers
Authors
Bushra Anjum , Shikha Mishra , Prince Maurya , Kishan Singh , Rohit Yadav
Keywords
Salmonella Typhimurium • Pathogenesis • Virulence factors • Host-pathogen interactions • Antibiotic resistance • Epidemiology
Abstract
Salmonella Typhimurium is a prominent pathogen causing numerous foodborne illnesses worldwide. This gram-negative bacterium is a subspecies of Salmonella enterica. Unlike typhoid fever, which is caused by Salmonella enterica serotype Typhi, S. Typhimurium is often transmitted through contaminated food and water. The resulting infection, called salmonellosis, manifests with gastrointestinal symptoms such as diarrhea, fever, abdominal cramps, and vomiting, typically within 6 to 72 hours after consumption. In severe cases, the infection can lead to invasive diseases like bacteremia and meningitis, posing significant risks to immunocompromised individuals, infants, and the elderly. The virulence of S. Typhimurium is primarily due to its various virulence factors, including adhesins, invasins, and toxins. These elements facilitate the bacterium's ability to attach to and invade epithelial cells, survive within host cells, and evade immune defenses. To confirm typhoid fever, isolating S. Typhi from bone marrow or blood cultures is the most reliable method. For diagnostic purposes, combining the Widal test with culturing S. Typhi from stool samples is commonly practiced. Recent advancements in genomic and proteomic technologies have enabled the identification of potential targets for new therapeutic and preventive measures, such as vaccines and antimicrobial agents. Controlling S. Typhimurium infections involves enhancing food safety practices, strengthening surveillance systems, and raising public awareness about correct food handling and preparation methods. Ongoing research is crucial to develop effective interventions and lessen the global impact of salmonellosis caused by Salmonella Typhimurium.
Downloads
How To Cite (APA)
Bushra Anjum, Shikha Mishra , Prince Maurya , Kishan Singh, & Rohit Yadav (July-2024). Clinical and Epidemiological Perspectives on Salmonella Typhimurium: A Comprehensive Review of Pathogenesis, Antibiotic Resistance, and Public Health Implications. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(7), a307-a320. https://ijnrd.org/papers/IJNRD2407085.pdf
Issue
Volume 9 Issue 7, July-2024
Pages : a307-a320
Other Publication Details
Paper Reg. ID: IJNRD_224687
Published Paper Id: IJNRD2407085
Downloads: 000121993
Research Area: Pharmacy
Country: Jaunpur , , utter Pradesh , India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2407085.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2407085
About Publisher
Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJNRD (IJ Publication) Janvi Wave | IJNRD.ORG | IJNRD.COM | IJPUB.ORG
Licence
This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
Publication Timeline
Article Preview: View Full Paper
Call For Paper
IJNRD is a Scholarly Open Access, Peer-reviewed, and Refereed Journal with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost Journal that follows UGC CARE 2025 Peer-Reviewed Journal Policy norms, Scopus journal standards, and Transparent Peer Review practices to ensure quality and credibility. IJNRD provides indexing in all major databases & metadata repositories, a citation generator, and Digital Object Identifier (DOI) for every published article with full open-access visibility.
The INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to advance applied, theoretical, and experimental research across diverse fields. Its goal is to promote global scientific information exchange among researchers, developers, engineers, academicians, and practitioners. IJNRD serves as a platform where educators and professionals can share research evidence, models of best practice, and innovative ideas, contributing to academic growth and industry relevance.
Indexing Coverage includes Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar (AI-Powered Research Tool), Microsoft Academic, Academia.edu, arXiv.org, ResearchGate, CiteSeerX, ResearcherID (Thomson Reuters), Mendeley, DocStoc, ISSUU, Scribd, and many more recognized academic repositories.
How to submit the paper?
By Our website
Click Here to Submit Paper Online
Important Dates for Current issue
Paper Submission Open For: October 2025
Current Issue: Volume 10 | Issue 10 | October 2025
Impact Factor: 8.76
Last Date for Paper Submission: Till 31-Oct-2025
Notification of Review Result: Within 1-2 Days after Submitting paper.
Publication of Paper: Within 01-02 Days after Submititng documents.
Frequency: Monthly (12 issue Annually).
Journal Type: IJNRD is an International Peer-reviewed, Refereed, and Open Access Journal with Transparent Peer Review as per the new UGC CARE 2025 guidelines, offering low-cost multidisciplinary publication with Crossref DOI and global indexing.
Subject Category: Research Area
Call for Paper: More Details
