The Role of Cancer Stem Cells in Tumor Relapse and Resistance: Mechanisms, Challenges, and Therapeutic Strategies

The Role of Cancer Stem Cells in Tumor Relapse and Resistance: Mechanisms, Challenges, and Therapeutic Strategies

Registration ID: IJNRD_224689

Published ID: IJNRD2407050

DOI: Click Here to Get

Roopal gupta

Cancer Stem cells, Mesenchymal Stem cells, Cancer relapse, Tumor Microenvironment, Chimeric antigen receptor

Cancer is a complex disease defined by altered gene expression. The core issue driving cancer development is the persistent, unregulated proliferation of cancer cells. These cells fail to respond to the signals that control normal cell behavior, leading to uncontrolled growth and division. As a result, cancer cells invade normal tissues and organs and eventually spread throughout the body. Cancer stem cells (CSCs) represent a small subpopulation within tumors with the capacity for self-renewal, differentiation, and tumor initiation when transplanted into an animal host. They play crucial roles in cancer relapse and metastasis. This review article highlights the complex nature of CSCs in cancer biology and the ongoing efforts to develop targeted therapies to overcome their contribution to tumor relapse and treatment resistance.

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"The Role of Cancer Stem Cells in Tumor Relapse and Resistance: Mechanisms, Challenges, and Therapeutic Strategies", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 7, page no.a471-a477, July-2024, Available :https://ijnrd.org/papers/IJNRD2407050.pdf

Volume 9 Issue 7, July-2024

Pages : a471-a477

Paper Reg. ID: IJNRD_224689

Published Paper Id: IJNRD2407050

Downloads: 000121185

Research Area: Life Sciences 

Country: Delhi, Delhi, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2407050.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2407050

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

Call For Paper - Volume 10 | Issue 8 | August 2025

IJNRD is Scholarly open access journals, Peer-reviewed, and Refereed Journals, High Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool), Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) with Open-Access Publications.

INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world. IJNRD will provide an opportunity for practitioners and educators of engineering field to exchange research evidence, models of best practice and innovative ideas.

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