Paper Title
Study of Tofacitinib citrate by using fourier transform infrared
Article Identifiers
Authors
Ashok.Shrikisan.Dhindule , Dr.Prachi.p.Udapurkar , B.S.Bhosale
Keywords
Infrared light source. Interferometer: Splits the IR light into two beams, modulates them, and recombines them to createan interferogram.
Abstract
Tofacitinib citrate, a Janus kinase inhibitor used in the treatment of rheumatoid arthritis and other inflammatory conditions, was analyzed using Fourier-transform infrared (FTIR) spectroscopy to elucidate its structural characteristics and confirm its chemical composition. The FTIR spectra of tofacitinib citrate were recorded in the range of 4000–400 cm^-1, revealing distinct absorption bands corresponding to various functional groups present in the molecule. The characteristic peaks at 3310 cm^-1 (N-H stretching), 2920 cm^-1 (C-H stretching), 1650 cm^-1 (C=O stretching), and 1240 cm^-1 (C-N stretching) were identified, confirming the presence of amide, aromatic, and aliphatic structures. This spectroscopic analysis provided a non-destructive and rapid method for the qualitative assessment of tofacitinib citrate, ensuring its purity and aiding in the quality control of pharmaceutical formulations. The results demonstrated the utility of FTIR spectroscopy in the pharmaceutical analysis of complex molecules like tofacitinib citrate.
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How To Cite (APA)
Ashok.Shrikisan.Dhindule, Dr.Prachi.p.Udapurkar, & B.S.Bhosale (July-2024). Study of Tofacitinib citrate by using fourier transform infrared. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(7), a110-a139. https://ijnrd.org/papers/IJNRD2407013.pdf
Issue
Volume 9 Issue 7, July-2024
Pages : a110-a139
Other Publication Details
Paper Reg. ID: IJNRD_224535
Published Paper Id: IJNRD2407013
Downloads: 000121990
Research Area: Pharmacy
Country: Beed, maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2407013.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2407013
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition


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