Paper Title
ASSESSMENT OF LIFESTYLE MODIFICATIONS FOR DIABETES MELLITUS
Article Identifiers
Authors
Kolanedi.Anupama Priyadarshini , B.Naga namratha reddy , V.Guru Keerthi , K.Sravani , K.Dedeepya, T.Lakshmi Vasanthi, K.Naga Phani kumar
Keywords
ASSESSMENT OF LIFESTYLE MODIFICATIONS FOR DIABETES MELLITUS
Abstract
The prevalence of diabetes, especially type 2 diabetes and hypertension are significantly increased with the prevalence of obesity . Type 2 diabetes, hypertension frequently associated with type 2 diabetes, and obesity are important risk factors for cardiovascular morbidity and mortality and cardiac- and renal complications. Hyperglycemia as well as hyperinsulinemia in type 2 diabetes is a cardiovascular risk by itself . Type 2 diabetes, hypertension and obesity are characterized by stimulation of the renin-angiotensinaldosterone system (RAAS), elevated sympathetic activity and insulin resistance. Importantly, these characteristics, themselves, are one of the cardiovascular risks. Therefore, pharmacological and non-pharmacological treatments for type 2 diabetes should be selected from favourable effects on stimulated RAAS, elevated sympathetic nervous system activity, insulin resistance and leptin resistance.Weight loss is recommended to delay and prevent type 2 diabetes in obesity, and for the treatment. Lifestyle modification such as a caloric restricted diet, reducing sedentary behaviour and an increase in exercise form the basis of all therapy. Weight loss treated with lifestyle modification including calorie restriction and/or exercise causes normalization of stimulated RAAS, sympathetic activation, insulin resistance, and hyperleptinemia, which are usually observed in type 2 diabetes and obesity. Recently, Straznicky et al. and Masuo et alhave shown the low caloric diet and exercise have different effects on insulin resistance, the RAAS, and sympathetic nervous activity in obese hypertensive subjects, although similar weight loss was observed between both interventions. Straznicky et al. reported that exercise had stronger effects of normalized the RAAS stimulation, sympathetic activation and insulin resistance compared to diet only, whereas Masuo et al. showed mild calorie restriction and mild exercise has different mechanisms on weight loss (normalization on sympathetic
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Kolanedi.Anupama Priyadarshini, B.Naga namratha reddy, V.Guru Keerthi, K.Sravani, & K.Dedeepya, T.Lakshmi Vasanthi, K.Naga Phani kumar (May-2024). ASSESSMENT OF LIFESTYLE MODIFICATIONS FOR DIABETES MELLITUS. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(5), g77-g97. https://ijnrd.org/papers/IJNRD2405610.pdf
Issue
Volume 9 Issue 5, May-2024
Pages : g77-g97
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Paper Reg. ID: IJNRD_222117
Published Paper Id: IJNRD2405610
Downloads: 000121984
Research Area: Engineering
Country: -, -, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2405610.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2405610
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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