A case report on hepatotoxicity associated with haloperidol

A case report on hepatotoxicity associated with haloperidol

Registration ID: IJNRD_222036

Published ID: IJNRD2405546

DOI: http://doi.one/10.1729/Journal.39530

Mohd Farhan Shehzad , Insharah Khan , Abhijith Murali , Hannan Husain , Mohd Alam

Haloperidol, RUCAM, Hepatotoxicity

A 55-year-old male with a decade-long history of schizophrenia had severe psychotic symptoms and was prescribed haloperidol. Three weeks later, he began experiencing signs of liver malfunction, such as dark urine, exhaustion, nausea, and moderate right upper quadrant abdominal discomfort, which was accompanied by jaundice. Laboratory studies revealed high levels of AST, ALT, ALP, and total bilirubin in the liver. Tests for viral hepatitis and autoimmune markers were negative, and an abdominal ultrasound revealed no evidence of biliary blockage. In Drug Induced Liver Injury (DILI), the Roussel Uclaf Causality Assessment Method (RUCAM) assigns points for clinical, biochemical, serologic, and radiologic features of liver injury, resulting in a comprehensive assessment score that reflects the possibility that the hepatic injury was caused by a specific medication.

Published Paper   E-Certificate

"A case report on hepatotoxicity associated with haloperidol", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 5, page no.f423-f428, May-2024, Available :https://ijnrd.org/papers/IJNRD2405546.pdf

Volume 9 Issue 5, May-2024

Pages : f423-f428

Paper Reg. ID: IJNRD_222036

Published Paper Id: IJNRD2405546

Downloads: 000121166

Research Area: Pharmacy

Country: Moradabad, Uttar Pradesh, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2405546.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2405546

DOI: http://doi.one/10.1729/Journal.39530

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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