Formulation and characterization of phytosomal gel by using amaltas for skin problem and as antipyretic

Formulation and characterization of phytosomal gel by using amaltas for skin problem and as antipyretic

Registration ID: IJNRD_220181

Published ID: IJNRD2405300

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Himanshu yadav , Abhay Pratap singh , Dhaneshwar kumar vishwakarma , Dr. Jai Narayan Mishra

Preparation, characterization, phytosomes, cassia fistula, phytosomal gel.

Novel drug delivery system is a new approach to drug delivery the shows the limitation of the traditional drug delivery system. The effectiveness of any herbal medication in depends on the delivery of effective level of the therapeutically active compound. These are improved forms of herbal formulation which contain the bioactive phytoconstituents of herb essence enclosed and bound by a lipid. Phytosomes demonstrated improved pharmacokinetic and pharmacodynamic response than botanical extract. Phytosomes is vesicular drug delivery system that proved to be beneficial in providing good absorption and better bioavailability over the herbal conventional extracts. The aim and objective of the study is to develop polyherbal phytosome gel by using amaltas (cassia fistula) extract. The amaltas are extracted with the help of ethanol by using soxhlet apparatus. The phytosomes are prepared by reflux method and their optimized. The formulation of phytosomes are analyzed for measurement of particle size and zeta potential, drug content, drug entrapment efficiency, percentage yield, in-vitro drug release studies. Then incorporate this phytosomal complex into gel formulation. Then the phytosomal gel formulations are evaluated by spread ability, drug content, measurement of pH, homogeneity, rheological studies.

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"Formulation and characterization of phytosomal gel by using amaltas for skin problem and as antipyretic", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 5, page no.c947-c953, May-2024, Available :https://ijnrd.org/papers/IJNRD2405300.pdf

Volume 9 Issue 5, May-2024

Pages : c947-c953

Paper Reg. ID: IJNRD_220181

Published Paper Id: IJNRD2405300

Downloads: 000121212

Research Area: Pharmacy

Country: Gorakhpur, Uttar pradesh, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2405300.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2405300

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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