Paper Title
PHYTOCHEMICAL SCREENING AND BIOLOICAL STUDIES OF Tetrataenium nepalense SEED EXTRACTS
Article Identifiers
Registration ID: IJNRD_218872
Published ID: IJNRD2404737
: http://doi.one/10.1729/Journal.39125
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Keywords
Tetrataenium nepalense, antibiotics, antioxidant, MBC
Abstract
Tetrataenium nepalense is a wild herb used traditionally to treat fever, common cold, cough etc. This plant takes three years to mature. The study investigates for antimicrobial, antifungal and antioxidant properties of Tetrataenium nepalense extract. This plant was extracted by maceration using ethanol. Then the percentage yield of extract was calculated. This plant was choose since it has historically been used to cure variety of ailments. The microscopic characteristics, extractive values and ash value of plant powder was done while UV spectrophotometry was used for the quantitative analysis, color change was the basis for the qualitative phytochemical screening. The extract contained phytochemicals such as alkaloids, steroids, quininone, coumarin, flavonoids, terpenoids, and carbohydrates, according to a preliminary phytochemical screening. The phenolic content was found to be 36.75 mg/g GAE and the flavonoid content was found to be 40.085 mg QE/g. The DPPH scavenging assay was carried out for antioxidant property and IC5O value was found to be 36.441379. During antibacterial screening, the extract was found to be effective against Bacillus subtilis and Staphylococcus aureus. This extract exhibited no antifungal action. For S. aureus, the minimum bactericidal concentration (MBC) was found to be between 25 and 50 mg/ml, while for Bacillius subtilis, it was found to be between 0.78125 and 1.5625 mg/ml. With its high quantity of total phenolic and total flavonoid content, the plant exhibits significant antioxidant activity. It also works well against gram-positive bacteria, which aids in the creation of narrow spectrum antibiotics. Therefore, this could be a potential lead molecule for antibiotics. Further research in Tetrataenium nepalense may lead to the discovery of the new molecule.
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How To Cite (APA)
Rakshya Bantawa Rai, Dr. Sabyata Gautam, Rajan Manandhar, & Mohan Pd. Amatya (April-2024). PHYTOCHEMICAL SCREENING AND BIOLOICAL STUDIES OF Tetrataenium nepalense SEED EXTRACTS. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(4), h302-h310. http://doi.one/10.1729/Journal.39125
Issue
Volume 9 Issue 4, April-2024
Pages : h302-h310
Other Publication Details
Paper Reg. ID: IJNRD_218872
Published Paper Id: IJNRD2404737
Research Area: Engineering
Author Type: Indian Author
Country: -, -, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2404737.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2404737
Crossref DOI: http://doi.one/10.1729/Journal.39125
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