Paper Title
A Review on Use of Glidants in Formulation of Pharmaceutical Solid dosage Forms
Article Identifiers
Authors
Mr. S. D. Paralkar , Dr. Y. S. Thorat , Dr. B. D. Tiwari , Ms. L. A. Kawade , Ms. R. P. Kinagi
Keywords
Glidants, Flow property, Surface charge, Cavity filling
Abstract
Glidants are the substances that enhance the flow characteristics of powder mixture. To get desired effect, these are added as a dry powder before the compression process. Glidants can show their effect at certain optimum concentration only. Above certain concentration glidants itself inhibit or decreases the good flow or flow properties. Glidants act by decreasing the overall surface charge present on the blend decreasing friction between particles and filling the gaps on the surface, thus further enhancing the rate of movement and flow. Glidants are additive materials that are used to improve a powder's flowability by lowering surface charge, cohesion, and interparticle friction all of which lower the angle of repose. Angle of repose is the maximum angle between the free standing surface of powder and horizontal plane. Smaller angle indicates a good flow property compared to bigger angle. Glidants also show impact on the flow properties, product quality, granulation, particle size, uniform distribution, tablet die cavity. Glidants play vital role in pharmaceutical industry for better quality of products. Various glidants used in pharmaceutical industry are Talc, Magnesium oxide, Magnesium silicate, Silicon dioxide, etc.
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How To Cite
"A Review on Use of Glidants in Formulation of Pharmaceutical Solid dosage Forms", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 4, page no.e127-e141, April-2024, Available :https://ijnrd.org/papers/IJNRD2404416.pdf
Issue
Volume 9 Issue 4, April-2024
Pages : e127-e141
Other Publication Details
Paper Reg. ID: IJNRD_218414
Published Paper Id: IJNRD2404416
Downloads: 000121347
Research Area: Pharmacy
Country: Solapur, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2404416.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2404416
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition


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