Paper Title
A Single Blind Clinical Trial to Evaluate the Efficacy of Unani Formulation in Hisath Ul Marara(Cholelithiasis)
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Registration ID: IJNRD_217486
Published ID: IJNRD2404251
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Keywords
Key Words: cholelithiasis, Hisat-e-Marara, Hisat- e-safravi, Gall stones, concretion.
Abstract
Introduction: Cholelithiasis (Hisat-e-Marara) is a crystalline concretion formed within the gall bladder by the accretion of bile components. Gallstone disease is a major health problem leading to Surgical intervention. Various biochemical and patho-physiological factors have been reported to be associated with gallstone disease such as stasis of bile, obstruction in the bile duct, infection in the bile, obesity, oestrogen level, defective function of liver and gallbladder, reduction in bile salt concentration and various precipitating factors for stone formation. In Unani literature this disease comes under the caption Hisat-e- Safravi or Hisat ul Marara which forms in biliary tract. According to unani physicianss the causes of gall stone formation are dame ghaliz. Zoaf quwate dafeya, shiddate quwate jaziba, congenital narrowing of biliary system, khilte ghaliz wa lazuj etc.Gall stones are quite prevalent in most western countries (10%-15%). It is estimated that at least 25 million persons in the United States have gall stones, less frequent in India around 4%. Women are affected more often than men in theratio of 4:1. It is observed that gall stone is more common in FATTY, FORTY, FERTILE andFEMALES i.e, 4Fs. Aim and Objectives: To assess the safety of unani compound formulation in cases of Hisath-ul-Marara. To evaluate the efficacy of unani compound formulation in the management of Hisath-ul-Marara. Methodology: The Study was conducted as a single blind clinical trial on 40 patients in speciality Outpatient Department, Post Graduate Department Of Moalijat, Govt. Nizamia Tibbi College and General Hospital, Hyderabad. 40 Patients allocated in a single group were given the test drug in form of joshanda of kulthi (7 gm) and Powder (5gm) of Khare khask, lahsun and Naushadar, twice daily up to 90 days with five follow-ups (15th,30th,45th, 60th, 75th and 90thday). The Pre and post treatment effects were assessed based on subjective and objective parameters. Results and conclusion: The Subjective parameters like Right Hypochondric pain, Nausea, Vomiting, Indigestion, Flatulence were reduced with statistical significance (P <0.0001), and the USG findings were changed with (P=0.0319). The Test drug is effective and is found safe without any adverse events during the study period.
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How To Cite (APA)
Dr.Syeda Sameen , Dr.Syed Abdul Khadir Hussaini, & Prof. Mohd Ahsan Faroqui (April-2024). A Single Blind Clinical Trial to Evaluate the Efficacy of Unani Formulation in Hisath Ul Marara(Cholelithiasis). INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(4), c199-c218. https://ijnrd.org/papers/IJNRD2404251.pdf
Issue
Volume 9 Issue 4, April-2024
Pages : c199-c218
Other Publication Details
Paper Reg. ID: IJNRD_217486
Published Paper Id: IJNRD2404251
Research Area: Medical Science
Author Type: Indian Author
Country: Hyderabad , Telangana , India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2404251.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2404251
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