Paper Title
Navigating Warfarin's Pharmacological Maze: A Review Of Drug-Drug Interactions
Article Identifiers
: Authors
Keywords
Warfarin, Anticoagulation therapy, Drug interactions, Pharmacokinetics, Pharmacodynamics, Cytochrome P450 enzymes, Vitamin K antagonists, INR (International Normalized Ratio), Clinical implications, Adverse effects.
Abstract
Warfarin, a commonly prescribed anticoagulant, has over 250 known drug interactions that can significantly impact its therapeutic efficacy and safety. These interactions can occur with various medications, dietary supplements, and food items, with approximately 120 drugs or foods interacting with warfarin. The concurrent use of potentially interacting drugs during warfarin therapy is a common practice, with about half of patients receiving warfarin being prescribed concomitant drugs with high potential for interactions. These interactions can interfere with the maintenance of the International Normalized Ratio (INR) within the therapeutic range, leading to an increased risk of bleeding events. Studies have shown that the risk of serious bleeding in patients treated with warfarin is significantly higher when they are using potentially interacting drugs, compared to those on warfarin alone. The influence of drug-drug interactions on the risk of cerebral hemorrhage induced by warfarin has also been investigated. In conclusion, warfarin drug interactions are of great clinical importance, as a large number of patients who take concomitant medications that can increase the INR or the risk of bleeding are at risk.
Downloads
How To Cite (APA)
Vishal K R & Syed Muhammad (March-2024). Navigating Warfarin's Pharmacological Maze: A Review Of Drug-Drug Interactions . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(3), e633-e639. https://ijnrd.org/papers/IJNRD2403478.pdf
Issue
Volume 9 Issue 3, March-2024
Pages : e633-e639
Other Publication Details
Paper Reg. ID: IJNRD_216355
Published Paper Id: IJNRD2403478
Downloads: 000122253
Research Area: Pharmacy
Author Type: Indian Author
Country: Bengaluru, Karnataka, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2403478.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2403478
About Publisher
Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
UGC CARE JOURNAL PUBLICATION | ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJNRD (IJ Publication) Janvi Wave | IJNRD.ORG | IJNRD.COM | IJPUB.ORG
Copyright & License
© 2025 — Authors hold the copyright of this article. This work is licensed under a Creative Commons Attribution 4.0 International License. and The Open Definition.
You are free to share, adapt, and redistribute the material, provided proper credit is given to the original author. 🛡️ Disclaimer: The content, data, and findings in this article are based on the authors’ research and have been peer-reviewed for academic purposes only. Readers are advised to verify all information before practical or commercial use. The journal and its editorial board are not liable for any errors, losses, or consequences arising from its use.
Publication Timeline
Article Preview: View Full Paper
Call For Paper
IJNRD is a Scholarly Open Access, Peer-Reviewed, Refereed, and UGC CARE Journal Publication with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost, and Transparent Peer Review Journal Publication that adheres to the UGC CARE 2025 Peer-Reviewed Journal Policy and aligns with Scopus Journal Publication standards to ensure the highest level of research quality and credibility.
IJNRD offers comprehensive Journal Publication Services including indexing in all major databases and metadata repositories, Digital Object Identifier (Crossref DOI) assignment for each published article with additional fees, citation generation tools, and full Open Access visibility to enhance global research reach and citation impact.
The INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to advance applied, theoretical, and experimental research across diverse academic and professional fields. The journal promotes global knowledge exchange among researchers, developers, academicians, engineers, and practitioners, serving as a trusted platform for innovative, peer-reviewed journal publication and scientific collaboration.
Indexing Coverage: Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar (AI-Powered Research Tool), Microsoft Academic, Academia.edu, arXiv.org, ResearchGate, CiteSeerX, ResearcherID (Thomson Reuters), Mendeley, DocStoc, ISSUU, Scribd, and many other recognized academic repositories.
How to submit the paper?
By Our website
Click Here to Submit Paper Online
You can now publish your research in IJNRD. IJNRD is a Transparent Peer-Reviewed Open Access Journal Publication (Refereed Journal), aligning with New UGC and UGC CARE recommendations.
For more details, refer to the official notice: UGC Public Notice
Submit Paper Online
Important Dates for Current issue
Paper Submission Open For: December 2025
Current Issue: Volume 10 | Issue 12 | December 2025
Impact Factor: 8.76
Last Date for Paper Submission: Till 31-Dec-2025
Notification of Review Result: Within 1-2 Days after Submitting paper.
Publication of Paper: Within 01-02 Days after Submititng documents.
Frequency: Monthly (12 issue Annually).
Journal Type: IJNRD is an International Peer-reviewed, Refereed, and Open Access Journal with Transparent Peer Review as per the new UGC CARE 2025 guidelines, offering low-cost multidisciplinary publication with Crossref DOI and global indexing.
Subject Category: Research Area
Call for Paper: More Details
Approval, Licenses and Indexing: More Details
