Analytical method development and validation of isoniazid and Rifampicin by RP HPLC Method

Analytical method development and validation of isoniazid and Rifampicin by RP HPLC Method

Registration ID: IJNRD_216422

Published ID: IJNRD2403460

DOI: Click Here to Get

Mr.Pritesh S. Mahajan , Dr.Vilas L Badgujar , Dr.Rajendra Wagh

Isoniazid,Rifampicin,validation

Isoniazid & Rifampicin both the drug use in combination for treatment of Tuberculosis (TB), Isoniazid is a first-line treatment for tuberculosis. It works by blocking the production of mycolic acid, which is a cell wall component in the tuberculosis bacterium while Rifampin acts via the inhibition of DNA-dependent RNA polymerase, leading to a suppression of RNA synthesis and cell death. Here we use RP-HPLC as an Analytical method for the drug i.e. Isoniazid and Rifampicin, by using Analytical Technique we develop and Validate the Isoniazid addrug, here we take UV Spectroscopy, Chromatogram of isoniazid and Rifampicin, We also carried out the Intraday and Inter day Precision studies on RP- HPLC for Isoniazid and Rifampicin.

Published Paper   E-Certificate

"Analytical method development and validation of isoniazid and Rifampicin by RP HPLC Method ", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 3, page no.e495-e502, March-2024, Available :https://ijnrd.org/papers/IJNRD2403460.pdf

Volume 9 Issue 3, March-2024

Pages : e495-e502

Paper Reg. ID: IJNRD_216422

Published Paper Id: IJNRD2403460

Downloads: 000121235

Research Area: Pharmacy

Country: Dhule, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2403460.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2403460

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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