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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | UNRAVELING HPLC MYSTERIES: A COMPREHENSIVE TROUBLESHOOTING GUIDE |
| Authors Name: | Vishwas Jibkate , Sanket Kurumkar , Sagar Raut , Nishant Awandekar , Milind Umekar |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_216044
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| Published Paper Id: | IJNRD2403434 |
| Published In: | Volume 9 Issue 3, March-2024 |
| DOI: | |
| Abstract: | ABSTRACT: “Unraveling HPLC Mysteries: A Comprehensive Troubleshooting Guide” delves into the intricacies of High-Performance Liquid Chromatography (HPLC) to offer a thorough roadmap for resolving common challenges chromatography encounters. HPLC is a cornerstone technique across diverse scientific domains, yet its effectiveness can be compromised by issues ranging from peak broadening to baseline instability. This review paper meticulously dissects these challenges, presenting an exhaustive array of potential sources and corresponding remedies. It navigates through critical aspects such as column selection, mobile phase optimization, sample preparation techniques, and instrument maintenance protocols. By comprehensively addressing each facet of HPLC troubleshooting, this guide empowers chromatographers to diagnose and rectify problems confidently and precisely. Additionally, it explores advanced strategies for enhancing method robustness and ensuring reproducibility, bolstering the reliability of chromatographic analyses. Through a synthesis of theoretical insights and practical wisdom garnered from real-world experiences, this guide illuminates the complexities of HPLC. It equips practitioners with the requisite expertise to overcome obstacles effectively. By demystifying the intricacies of HPLC troubleshooting, this paper serves as an invaluable resource for researchers, analysts, and students alike, fostering a deeper understanding of chromatographic principles and facilitating advancements in analytical chemistry and related fields. |
| Keywords: | HPLC, Detector, Sample Preparation, Troubleshooting |
| Cite Article: | "UNRAVELING HPLC MYSTERIES: A COMPREHENSIVE TROUBLESHOOTING GUIDE", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 3, page no.e271-e284, March-2024, Available :http://www.ijnrd.org/papers/IJNRD2403434.pdf |
| Downloads: | 00037 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2403434 Registration ID: 216044 Published In: Volume 9 Issue 3, March-2024 DOI (Digital Object Identifier): Page No: e271-e284 Country: Nagpur, Maharashtra , India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2403434 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2403434 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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