Paper Title
Diagnosis, treatment and management of hereditary nonpolypsis colorectal cancer (HNPCC)
Article Identifiers
Authors
Gadade Pooja Nandakumar , Dahifale Dnyaneshwari
Keywords
hereditary non-polyposis colorectal cancer, Lynch syndrome, surveillance, Management, Treatment, Diagnosis.
Abstract
Hereditary nonpolyposis colorectal cancer (HNPPCC) may be a commonplace familial cancer that’s one of autosomal overwhelming acquired illnesses. Since endometrial cancer happens as often as possible in ladies with HNPCC, a few endometrial cancers, like HNPCC, are familial cancers caused by changes within the DNA bungle repair (MMR) quality. It is observed that to get it the clinical pathology of familial endometrial cancer associated with HNPCC, we examined the family history of 385 endometrial cancer patients and found that 0.5% of endometrial cancer patients met the unused symptomatic criteria for her HNPCC. It turned out to meet. Atomic and organic analyzes found microsatellite insecurity in 30.8% of endometrial think about cancers and germline mutations in MMR qualities in 8.3% of . These comes about show that there’s a near relationship between MMR quality changes and the improvement of endometrial cancer. To superior get it the clinical pathology of HNPCC associated familial endometrial cancer, it is vital for gynecologists to conduct large-scale multicenter considers that incorporate a complete family history.this study contains the diagnosis, surveillance and treatment of the HNPCC.
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How To Cite (APA)
Gadade Pooja Nandakumar & Dahifale Dnyaneshwari (February-2024). Diagnosis, treatment and management of hereditary nonpolypsis colorectal cancer (HNPCC). INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(2), d236-d241. https://ijnrd.org/papers/IJNRD2402324.pdf
Issue
Volume 9 Issue 2, February-2024
Pages : d236-d241
Other Publication Details
Paper Reg. ID: IJNRD_214430
Published Paper Id: IJNRD2402324
Downloads: 000121978
Research Area: Pharmacy
Country: Ahmednagar , Maharastra , India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2402324.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2402324
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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