Liposomes as targeted drug delivery systems in the treatment of breast cancer.

Registration ID: IJNRD_214266

Published ID: IJNRD2402251

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Revati Ravindra Deshmukh, Amruta Lala Ghodake, Mr. Sukumar Maruti Lande, Dr. Rupali R. Bendgude

liposomes, drug delivery systems, cancer therapy.

Solid tumors such as breast cancer have historically provided many challenges to anti-cancer therapy. Therapeutic hurdles to drug penetration in solid tumors include heterogeneous vascular supply and high interstitial pressures within tumor tissue, particularly in necrotic zones, lower pH and presence of leaky vasculature leading to reduced therapeutic response. Liposome based drug delivery systems offer the potential to enhance the therapeutic index of anti-cancer agents, either by increasing the drug concentration in tumor cells and by decreasing the exposure in normal tissues exploiting enhanced permeability and retention effect phenomenon and by utilizing targeting strategies. This review discusses recent trends in liposome-based drug delivery system both for diagnosis and treatment of breast cancer.

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Revati Ravindra Deshmukh, Amruta Lala Ghodake, Mr. Sukumar Maruti Lande, & Dr. Rupali R. Bendgude (February-2024). Liposomes as targeted drug delivery systems in the treatment of breast cancer.. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(2), c441-c447. https://ijnrd.org/papers/IJNRD2402251.pdf

Volume 9 Issue 2, February-2024

Pages : c441-c447

Paper Reg. ID: IJNRD_214266

Published Paper Id: IJNRD2402251

Downloads: 000122255

Research Area: Pharmacy

Author Type: Indian Author

Country: Solapur, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2402251.pdf

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