INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Recently, the focus of research has shifted to the creation of environmentally acceptable processes for the synthesis of metallic nanostructures. A surface-sensitive approach called surface-enhanced Raman scattering (SERS) increases Raman scattering by molecules adsorbed on rough metal surfaces. The development of biosensors and biocatalysts is known to be greatly influenced by the SERS properties of metal nanoparticles, particularly gold and silver nanoparticles. Here, we report the biosynthesis of gold nanoparticles with good SERS capabilities utilising the sweet orange (Citrus Sinensis) extract as a target molecule, enhancing Raman signals up to several times. By simply heating the mixture of tetrachloroauric acid solution (HAuCL4) and orange extract at 80 0C for one hour, spherical mono-dispersed AuNPs with a very wide size range (5 - 50 nm) were produced. The characteristic plasmon resonance peak, morphological and aggregate characteristics, elementary composition, and other parameters were detected using the ultraviolet-visible (UV-vis) spectrophotometer, transmission electron microscopy (TEM), energy-dispersive spectroscopy (EDS), x-ray diffraction analysis (XRD), and x-ray photoelectron spectroscopy (XPS). To identify the elements that contribute to the reduction and stability of AuNPs, the fourier transform infrared (FT-IR) spectrophotometer was used to assess the main functional groups in the extract. In order to determine the toxicity of the produced AuNPs, a hemolysis test for their aqueous solution was carried out. The results showed a low hemolysis percentage (less than 1 percent), which denotes their non-toxic nature. These "green" produced gold nanoparticles may find use in biological sensing and other biological applications, according to the data given here, because of their great biocompatibility.
Keywords:
Gold nanoparticles, green synthesis, SERS, hemolysis
Cite Article:
"Green synthesis of biologically benign SERS active gold nanoparticles", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 2, page no.b107-b114, February-2024, Available :http://www.ijnrd.org/papers/IJNRD2402115.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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